结论成功建立了OPG基因修饰的骨髓基质细胞瞬时基因表达体系。
Conclusion The transiently expression system of BMSCs modified by OPG gene is successfully established.
目的探讨地塞米松对体外培养的骨髓基质细胞增殖和分化等生物学特性的影响。
OBJECTIVE: To investigate the effects of dexamethasone on the proliferation and differentiation of bone marrow stromal cells.
提取的骨髓基质细胞呈贴壁生长,诱导后可向成骨细胞分化,细胞呈成骨细胞形态为梭形和多角形。
BMSC grew by static adherence, differentiated to osteoblasts and had strong capacity of proliferation, the shape of cells was fusiform or polygon, like osteoblasts.
结论人脱细胞骨复合经诱导的骨髓基质细胞在体外具有有效的成骨功能,是一种较为理想的骨组织工程材料。
Conclusion HAB loaded with induced BMSCs has an excellent osteogenic function in vitro and presents an effective potential to be a good bone tissue engineering material.
结论:人脱细胞骨复合经诱导的骨髓基质细胞在体外具有有效的成骨功能,是一种较为理想的骨组织工程材料。
CONCLUSION: HAB loaded with induced BMSCs has an excellent osteogenic function in vitro and shows an effective potential as a good bone tissue engineering material.
目的:研究人脱细胞骨复合经诱导的骨髓基质细胞的实验效果,观察细胞的黏附和生长情况,并对其成骨活性进行检测。
OBJECTIVE: To investigate the experimental effect of HAB loaded with induced BMSCs, and observe the cellular adherence and growth as well as detect its osteoblastic activity.
目的:探讨白细胞介素6 (IL - 6)基因转染的骨髓基质细胞系qxmsc1 IL - 6对骨髓移植后造血功能的重建作用。
Objective: to study the effect of the IL-6 transfected bone marrow stromal cell, QXMSC1 IL-6, on the hematopoietic reconstitution in bone marrow transplanted mice.
资料综合:脂肪组织来源干细胞与同样起源于中胚层的骨髓基质细胞不仅具有非常相似的生物学特性,而且在细胞表面标志谱的表达方面也非常相近。
DATA SYNTHESIS: There was similar bionomics of adipose tissue-derived stem cells and bone mesenchymal cells, and the cell-surface marker spectrum was also very similar.
方法:将地塞米松诱导后的骨髓基质细胞种植在1%海藻酸盐中,以HE染色、BMP2免疫组化染色、扫描电镜观察骨髓基质细胞在凝胶中的生物学行为。
Method: Bone marrow stromal cells induced by Dexamethason were implanted in 1% concentrate alginate, and were stated by method of he stain, BMP 2 immunity histochemical stain and SEM.
目的:探讨胎儿骨髓基质细胞与外源性细胞因子的协同造血支持作用。
Objective: to elucidate the role of bone marrow stromal cells in cooperation with exogenous cytokines in hematopoiesis.
骨髓基质细胞源神经干细胞可通过向损伤脑区的迁移而发挥治疗作用。
They exert the therapeutic action on brain stem injuries by way of immigrating to the injured brain areas.
结论:体外培养的大鼠骨髓基质细胞移植在大鼠骨髓内能够至少存活12周,并在脊髓损伤处发挥一定的修复功能。
CONCLUSION: the cultured bone marrow stomal cells in vitro can survive for 12 weeks at least in the spinal cord of rats, and repair the injured spinal cord to some extent.
目的:研究兔活性骨组织在共培养条件下对同种骨髓基质细胞来源成骨细胞黏附特性的影响。
AIM: To investigate the effects of rabbit living bone tissue by co-culture on adhesion characteristics of homogeneous osteoblasts from bone marrow stromal cell.
小鼠骨髓基质细胞中内皮细胞和巨噬细胞的比例及总数明显高于人。
The percentage of murine bone marrow endothelial cells and macrophages was significantly higher than that of human.
细胞实验显示骨髓基质细胞在这种多孔材料的表面和孔隙中生长良好。
Cell test showed that bone marrow stromal cells can growth on the surface and in the porosity of this kind of glass-ceramic.
目的探讨一种较为有效的诱导方法将骨髓基质干细胞体外定向诱导分化为类许旺细胞。
Objective To search for a more efficient method to induce bone marrow stromal cells (BMSCs) into Schwann-liked cells (SLCs) in vitro.
这些生物刺激信号可影响植入支架内的间充质干细胞(msc)或骨髓基质细胞(BMSC),从而形成面部重建所需的组织。
These biologic cues should influence scaffold implanted mesenchymal stem cells (MSC) or bone marrow stromal cells (BMSC) to form the necessary tissue for site specific facial reconstruction.
目的:探讨自体骨髓基质干细胞修复兔桡骨远端骨缺损的可行性。
OBJECTIVE:To explore the feasibility on repairing bone defect of rabbit radius by autologous bone marrow stem cells.
结论:骨髓基质细胞对于背根神经节细胞的活力以及神经突起生长有一定的促进作用。
Conclusion: Bone marrow stromal cells play an important role in promoting the vitality and growth of dorsal root ganglia cells.
目的观察超低温冻存对人骨髓基质干细胞(BMSC)生物学特性的影响。
Objective To study the effects of cryopreservation on biological characters of human bone marrow stromal cell (BMSC).
目的:探讨温固化水凝胶作为骨髓基质干细胞的载体修复软骨缺损的可行性。
Objective To investigate the feasibility of the temperature dependent hydrogel loading bone marrow stromal cells for repairing articular cartilage defects.
若某种药物能够对抗乙醇诱导骨髓基质细胞的成脂分化作用,则可能防治酒精性骨坏死。
If a drug can resist the differentiation of MSCs into adipocytes induced by alcohol, it can prevent and treat alcohol-induced osteonecrosis.
目的:观察放烧复合伤小鼠骨髓基质细胞体外集落生成能力的变化。
Objective: To investigate the changes of cultured bone marrow stromal cells after combined radiationburn injury in mice.
结果:二甲胺四环素在体外具有刺激骨髓基质细胞和成骨细胞增殖的作用,但抑制细胞的分化。
Result: minocycline can stimulate the proliferation of osteoblast and marrow stromal cell, but also can restrain the differentiation.
结论:辛伐他汀促进骨髓基质细胞的分化,提高其矿化能力,有助于骨质疏松症的防治。
Conclusion: We confirmed that simvastatin promote differentiation and capacity of mineralization of BMSC and contribute to the prevention and treatment of osteoporosis.
目的研究软骨分化形成蛋白- 2 (CDMP - 2)对小鼠骨髓基质干细胞软骨分化的作用。
Objective To study the cartilage differentiation of mouse mesenchymal stem cells (MSCs) induced by cartilage-derived morphogenetic proteins-2 (CDMP-2) in vitro.
结果原代的小鼠培养骨髓基质细胞能很好的维持精原干细胞的非分化性扩增。
The feeder layers of bone marrow stromal cells allowed spermatogonial stem cells to proliferate well and remain undifferentiated.
目的探讨骨髓基质细胞分化为成骨表型的诱导条件。
ObjectiveTo explore environmental conditions under which bone marrow stromal cells could be induced into osteogenic phenotype.
目的:探讨同种异体骨髓基质细胞移植修复兔桡骨缺损的效果和免疫学变化。
Objective To investigate the therapeutic effect and immunological reaction of allogeneic bone marrow stromal cells transplantation for the repair of radial bone defect.
目的:探讨同种异体骨髓基质细胞移植修复兔桡骨缺损的效果和免疫学变化。
Objective To investigate the therapeutic effect and immunological reaction of allogeneic bone marrow stromal cells transplantation for the repair of radial bone defect.
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