不清楚原始肿瘤的雌激素受体状态是否影响HRT疗法期间复发的风险。
It is not clear if the estrogen receptor status of the original tumour influences the risk of recurrence with HRT use.
当它与其它组织如生殖系统组织中的雌激素受体结合时,对与生殖相关的功能没有影响。
When it binds to estrogen receptors in other tissues, such as reproductive tissues, it has no effect on their reproduction-related functions.
研究大脑其他区域的雌激素受体增加所带来的影响对弄清记忆处理的某些过程有所帮助。
Studying the effects of increasing the estrogen receptor in other brain regions may shed additional light on memory processes.
结论:胶艾汤及其加味方参芪胶艾汤具有一定的雌激素受体亚型特异性的雌激素样作用。
Objective:To study the phytoestrogenic effects of Jiaoaitang and Shenqi jiaoaitang through the tests of expression of estrogen receptor subtypes in mice.
如这类反应是发生在雌激素依赖性肿瘤细胞内的雌激素受体上,可能会有抑制肿瘤生长的作用。
If these reactions occurred on the estrogen receptors in the cells of estrogen-dependent tumors, the growth of tumors may be inhibited.
方法:利用免疫组织化学方法对6 5例婴幼儿口腔颌面部血管瘤标本的雌激素受体(ER)进行检测。
Methods:65 specimens of oral and maxillofacial hemangioma were studied with immunohistochemical techniques for the expression of estrogen receptor (ER).
综述近几年上市或开发中的雌激素受体调节剂类药物,主要包括选择性雌激素受体调节剂和纯抗雌激素药物。
The estrogen receptor modulator drugs launched or developed in recent years were reviewed, mainly including selective estrogen receptor modulators and pure antiestrogen.
研究人员发现在啮齿类动物中有一种被称为27-羟基胆甾醇或27HC的小分子,它可与心脏血管内的雌激素受体结合。
The researchers found that in rodents, a molecule called 27-hydroxycholesterol, or 27HC, binds to the same receptors in the blood vessels of the heart to which estrogen binds.
我们的资料显示GPR30促进的肿瘤生长,可能与肿瘤转移有关,但证据也显示了GPR30的自主性,不依赖于标准的雌激素受体。
"Our data indicates that GPR30 promotes tumor growth and is linked to metastatic disease, but also evidences GPR30's autonomy from the standard estrogen receptors," says Filardo.
而缺少雌激素受体的雌性老鼠生来指爪就更长,那些没有雄激素老鼠的指爪则更短,并且非常女性化。
Female mice that lacked an estrogen receptor were born with longer digits, and those that did not have testosterone had shorter, superfeminine digits.
而没有雌激素受体的雄性老鼠的无名指则更长。
Male mice without estrogen receptors had longer ring digits.
首先,他们用基因手段禁止了细胞受体的活动——细胞受体即那些向其他细胞发送和从其他细胞接受信号的分子们——因为雌激素和雄激素存在于正在发育的老鼠胚胎的肢芽中。
First, they used genetic tools to deactivate cell receptors-molecules that send and receive signals to and from other cells-for testosterone and estrogen in the developing limb buds of mouse embryos.
研究者在一段时间内训练小鼠找出一个隐藏到微型游泳槽内的平板,缺乏雌激素受体的小鼠的学习能力很差。
Mice that lacked the estrogen receptor showed poor ability to locate a platform hidden in a small swimming tank over a training period of several days.
此外,在ER+/PR+(雌激素受体阳性/孕激素受体阳性)恶性肿瘤和接受阿那曲唑作为内分泌治疗的患者中,发现了(大豆异黄酮和绝经妇女乳腺癌复发率之间)相反的关联。
Additionally, inverse associations were found in those who wee diagnosed with ER+/PR+ malignancy and those who receiving anastrozole as endocrine therapy.
根据这项新的研究,的确,对雌激素受体阳性肿瘤和雌激素受体阴性肿瘤的妇女都有利。
According to this new study, yes, it is beneficial to both women who have estrogen receptor positive tumors and estrogen receptor negative tumors.
在卵巢的内分泌调控中,雌激素受体发挥着重要的生理作用。
Estrogen Receptor play key role in the endocrine regulation of ovary.
通过该款应用,乳腺癌患者可输入和跟踪病症及治疗情况的详细信息,比如肿瘤的大小和雌激素受体的有无等。
Using this app, breast-cancer patients enter and track details of their disease and treatment, from the size of the tumor to the presence or absence of estrogen receptors.
结论:染料木黄酮不是通过促进雌激素受体基因和蛋白的表达来促进成骨细胞增殖。
CONCLUTION Genistein promotes the proliferation of osteoblast not through promoting the expression of estrogen receptor gene and protein.
从技术应用远景来看,他们导入雌激素受体的技术对于研究大脑中甾体激素受体功能是一大进步。
From a technology perspective, their technique to transfect the estrogen receptor is an exciting advance for researching steroid receptors in the brain.
本文就雌激素及其受体信号转导途径的相关国内外研究进展作一综述。
This article reviews the advance of estrogen and its receptors signal transduction pathway in abroad and domestic.
雌激素与血管内的受体结合通常可使血管壁保持弹性和处于扩张状态,并与其它心脏保护机制一同修复受损的脉管系统。
The normal result of this estrogen binding is that blood vessel walls remain elastic and dilated, and damage to the vasculature is repaired, among other heart-protective effects.
在此模型中,更高的临床肿瘤分级及雌激素受体阴性与远处复发或死亡存在具有显著统计学差异的相关性。
In this model, higher clinical tumor stage and ER-negative status were associated with a statistically significantly greater risk for distant relapse or death.
本研究证实了髁突软骨中存在雌激素受体的作用机制。
The study indicated the estrogen receptor mediating mechanism in the condylar cartilages.
据《自然遗传学》报道,研究人员宣称2号染色体和16号染色体发生基因变异会增加雌激素受体阳性的乳腺癌发病率。
Reporting in Nature Genetics, researchers said genetic variants on chromosome 2 and on chromosome 16 May increase the risk of estrogen-receptor-positive breast cancer.
在治疗的第3年,雌激素受体阳性患者获得97%的无远处复发生存率,绝对危险度大幅下降11%。
At 3 years, ER-positive patients achieved a DRFS of 97% and a significant absolute risk reduction of 11%.
这两种情况肿瘤样本的对比也许可以解释为什么一些雌激素受体阳性乳腺癌患者对降雌激素药物有效而有些却效果很差。
Comparing the two groups might help explain why some estrogen-receptor-positive breast cancer patients do well with estrogen-lowering drugs and others poorly.
目的建立一种灵敏度高、特异性强的细胞内雌激素受体检测方法。
Objective: To find a highly sensitive and specific method by which estrogen receptor in cells can be assayed.
抗雌激素疗法是雌激素受体依赖性乳腺癌内分泌疗法的重要手段之一。
Antiestrogens have been proven to be highly effective in the treatment of estrogen receptor-dependent breast cancer.
抗雌激素疗法是雌激素受体依赖性乳腺癌内分泌疗法的重要手段之一。
Antiestrogens have been proven to be highly effective in the treatment of estrogen receptor-dependent breast cancer.
应用推荐