• 他们发现用DADS治疗时,有名肿瘤抑制基因p53阻止细胞循环

    They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.

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  • 因此XAF1一个肿瘤抑制基因有可能成为肿瘤治疗靶向基因

    Thus XAF1 is a new cancer inhibiting gene and may become a new target to treat carcinoma.

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  • 甲基化抑制基因包括通过其它方式预防肿瘤生长扩散肿瘤抑制基因

    Genes suppressed by this methylation include tumor suppressors that would otherwise prevent cancer growth and spread.

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  • 原癌基因突变导致过度刺激细胞周期突变肿瘤抑制基因导致这一功能控制过度活动

    Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.

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  • 一种深圳百诺基因技术公司――一家中国公司,所使用方法就是正常肿瘤抑制基因置换破损的肿瘤抑制基因

    One approach, used by Shenzhen SiBiono GeneTech, a Chinese company, is to replace broken tumour-suppressor genes with the correct version.

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  • 通过甲基化或重新激活DNA甲基化所沉默肿瘤抑制基因它们可能干细胞重新编程和癌症研究提供非常重要信息。

    It could also inform cancer research, as it could give scientists the opportunity to reactivate tumor suppressor genes that had been silenced by DNA methylation.

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  • 研究人员瞄准进一步改善NMD -CGH基因芯片技术将之应用于发现前列腺以及其它癌症尚未被发现的肿瘤抑制基因

    The researches aim to develop the NMD-CGH microarray method further and apply it for new tumour-suppressor gene discovery approaches in prostate cancer and other cancer types.

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  • 2005年,斯隆·凯特琳中心研究人员曾报道了在另一种叫做P53肿瘤抑制基因关闭基因甚至仍然可以阻止前列腺癌肿瘤生长

    In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.

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  • 2005年,斯隆·凯特琳中心研究人员曾报道了另一种叫做P 53肿瘤抑制基因关闭,该基因甚至仍然可以阻止前列腺癌大肿瘤生长

    In 2005, researchers at Sloan-Kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as P53, was turned off.

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  • 称之为肿瘤抑制基因突变可以引起生长失去控制从而可能导致癌症

    Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.

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  • 良好生活习惯可以抑制引发肿瘤基因(致癌基因)发挥作用,其中一些致癌基因还是目前正在开发抗癌药物研究对象

    The good life turned off tumour-promoting genes (known as oncogenes) -including several that are the target of efforts to develop anti-cancer drugs.

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  • 其他基因突变可以抑制肿瘤,是人体对抗基因突变而产生危险天然防御机制。

    The other mutated genes seemed to be tumor suppressors, the body's natural defense against dangerous genetic mistakes.

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  • 该药物能够准确正确染色体数目导入一新细胞产生整倍体细胞,能够用于治疗由于肿瘤抑制基因突变导致肿瘤

    Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.

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  • 虽然许多基因肿瘤抑制基因广泛表达这些基因突变特定器官细胞类型有关

    Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.

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  • 探讨肿瘤抑制基因癌细胞生长抑制作用

    To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.

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  • 胶质母细胞9染色体肿瘤抑制基因研究

    A study of tumor suppressor genes on chromosome 9 in glioblastomas.

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  • 这种染色体异常使控制细胞生长关键肿瘤抑制基因失活。

    Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.

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  • NF 1基因突变导致肿瘤抑制异常,可发生各种各样良性恶性肿瘤

    The genetic mutation of the NF1 leads to abnormal tumor suppression, leading to a variety of benign and malignant tumors.

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  • 探讨肿瘤抑制基因杂合性缺失(LOH)原发性淋巴瘤(PHL)发生中作用

    Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).

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  • 方法建立卵巢癌裸鼠动物模型检测腺病毒介导血管抑素基因肿瘤生长抑制作用

    Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.

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  • SIPA1在HCC中发挥肿瘤抑制基因作用,抑制HCC复发转移有重要作用。

    SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.

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  • 肿瘤转移抑制基因抑制肿瘤细胞转移,由于肿瘤转移抑制基因突变缺失,从而导致肿瘤浸润转移。

    Tumor metastasis suppressor gene can inhibit the metastasis of tumor cells, mutations or deletions of this kind of genes can lead to tumor invasion and metastasis.

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  • 基因肿瘤抑制基因发现促进了对细胞周期细胞凋亡机制深入理解。使人们肿瘤发生发展认识日趋深入。

    The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.

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  • KRAS基因突变恶性肿瘤组织中频发,预测细胞肺癌分子靶向治疗疗效预后针对RAS基因分子抑制剂研究处于初级阶段。

    KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.

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  • 探讨直肠癌组织中脑特异性血管生长抑制因子1 (BAI1)基因表达情况及BAI1对肿瘤血管生成肿瘤生长作用

    Objective to explore the expression of brain-specific angiogenesis inhibitor 1 (BAI1) gene in rectal cancer tissues and its effect on growth and angiogenesis of the tumor.

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  • 综述了一些基因肿瘤抑制基因DNA修复基因细胞电离辐射敏感性影响

    Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.

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  • 第10染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因,可以负性调节肿瘤细胞生长

    As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.

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  • 选择肿瘤细胞特异表达基因特异性抑制表达,是靶向诱导肿瘤细胞凋亡关键。

    To induce tumor cell apoptosis effectively, we should select tumor cell- specific gene and inhibit its expression specifically.

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  • TGF配体虽然早期肿瘤作为肿瘤抑制基因发挥作用,其在进展肿瘤变成有效转移因子

    TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.

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  • 肿瘤转移过程研究中,许多证据已经证实了肿瘤转移抑制基因重要性

    Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes.

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