他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
因此,XAF1是一个新的肿瘤抑制基因,有可能成为肿瘤治疗的新靶向基因。
Thus XAF1 is a new cancer inhibiting gene and may become a new target to treat carcinoma.
被该甲基化抑制的基因包括通过其它方式预防肿瘤生长与扩散的肿瘤抑制基因。
Genes suppressed by this methylation include tumor suppressors that would otherwise prevent cancer growth and spread.
原癌基因的突变导致的过度刺激细胞周期,而突变的肿瘤抑制基因,会导致在这一功能的控制过度活动。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
一种由深圳赛百诺基因技术公司――一家中国公司,所使用的方法就是用正常的肿瘤抑制基因置换破损的肿瘤抑制基因。
One approach, used by Shenzhen SiBiono GeneTech, a Chinese company, is to replace broken tumour-suppressor genes with the correct version.
通过去甲基化或重新激活DNA甲基化所沉默的肿瘤抑制基因,它们可能为干细胞重新编程和癌症研究提供非常重要的信息。
It could also inform cancer research, as it could give scientists the opportunity to reactivate tumor suppressor genes that had been silenced by DNA methylation.
研究人员瞄准进一步改善NMD -CGH基因芯片技术,并将之应用于发现前列腺癌以及其它癌症的尚未被发现的肿瘤抑制基因。
The researches aim to develop the NMD-CGH microarray method further and apply it for new tumour-suppressor gene discovery approaches in prostate cancer and other cancer types.
早在2005年,斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P53的肿瘤抑制基因关闭时,该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massive tumor growth in prostate cancer even when another tumor suppressor, known as P53, was turned off.
早在2005年,斯隆·凯特琳中心的研究人员就曾报道了在另一种叫做P 53的肿瘤抑制基因关闭时,该基因甚至仍然可以阻止前列腺癌大肿瘤生长。
In 2005, researchers at Sloan-Kettering reported that the gene could stop massie tumor growth in prostate cancer een when another tumor suppressor, known as P53, was turned off.
称之为肿瘤抑制基因的突变可以引起生长失去控制,从而可能导致癌症。
Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
良好的生活习惯可以抑制引发肿瘤的基因(即:致癌基因)发挥作用,其中的一些致癌基因还是目前正在开发的抗癌药物的研究对象。
The good life turned off tumour-promoting genes (known as oncogenes) -including several that are the target of efforts to develop anti-cancer drugs.
其他的基因突变可以抑制肿瘤,是人体对抗因基因突变而产生危险的天然防御机制。
The other mutated genes seemed to be tumor suppressors, the body's natural defense against dangerous genetic mistakes.
该药物能够准确的将正确的染色体数目导入每一新细胞,产生非整倍体细胞,能够用于治疗由于肿瘤抑制基因突变导致的肿瘤。
Drugs that inhibit accurate delivery of the right number of chromosomes to each new cell, resulting in aneuploidy, would be used to destroy tumors caused by mutations in the tumor suppressors.
虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
探讨肿瘤抑制基因对肺腺癌细胞生长的抑制作用。
To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.
胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
A study of tumor suppressor genes on chromosome 9 in glioblastomas.
这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。
Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.
NF 1基因突变导致肿瘤抑制异常,可发生各种各样的良性和恶性肿瘤。
The genetic mutation of the NF1 leads to abnormal tumor suppression, leading to a variety of benign and malignant tumors.
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
方法建立人卵巢癌裸鼠动物模型,检测腺病毒介导的人血管抑素基因对肿瘤生长的抑制作用。
Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.
SIPA1在HCC中发挥肿瘤抑制基因的作用,且对抑制HCC的复发转移有重要作用。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
肿瘤转移抑制基因能抑制肿瘤细胞的转移,由于肿瘤转移抑制基因的突变或缺失,从而导致肿瘤的浸润和转移。
Tumor metastasis suppressor gene can inhibit the metastasis of tumor cells, mutations or deletions of this kind of genes can lead to tumor invasion and metastasis.
癌基因,肿瘤抑制基因的发现促进了对细胞周期及细胞凋亡机制的深入理解。使人们对肿瘤发生和发展的认识也日趋深入。
The discovery of oncogene and tumor suppressor gene has deepened human beings understanding of the mechanisms of cell cycle and cell apoptosis as well as the mechanisms of tumorigenesis.
KRAS基因突变在恶性肿瘤组织中频发,可预测非小细胞肺癌分子靶向治疗的疗效和预后,针对RAS基因的分子抑制剂研究仍处于初级阶段。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
目的探讨直肠癌组织中脑特异性血管生长抑制因子1 (BAI1)基因的表达情况及BAI1对肿瘤血管生成和肿瘤生长的作用。
Objective to explore the expression of brain-specific angiogenesis inhibitor 1 (BAI1) gene in rectal cancer tissues and its effect on growth and angiogenesis of the tumor.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因,可以负性调节肿瘤细胞的生长。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
选择肿瘤细胞特异表达基因并特异性地抑制其表达,是靶向诱导肿瘤细胞凋亡的关键。
To induce tumor cell apoptosis effectively, we should select tumor cell- specific gene and inhibit its expression specifically.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用,但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
目的:在肿瘤转移过程的研究中,许多证据已经证实了肿瘤转移抑制基因的重要性。
Purpose: Ample evidence supports an important role of tumor metastasis suppressor genes in cancer metastatic processes.
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