“我们惊讶地得到了死亡受体，它不会对任何激素产生反应，因为以前那些同样的状态在蛋白质中只存在很短的时间。”桑顿说道。
"We were surprised to get a dead receptor that wouldn't respond to any hormones, because those same states had existed in the protein a relatively short time before," says Thornton.
在此模型中，更高的临床肿瘤分级及雌激素受体阴性与远处复发或死亡存在具有显著统计学差异的相关性。
In this model, higher clinical tumor stage and ER-negative status were associated with a statistically significantly greater risk for distant relapse or death.
近年来对凋亡发生和调控机制的研究表明，细胞凋亡途径主要有两条：线粒体途径和死亡受体途径。
In recent years, studies of occurrence and regulation mechanism of apoptosis show that the two major apoptotic pathways are the mitochondrial and death receptor pathways.
因谷氨酸代谢异常，过度释放和对突触后受体的高频刺激，引起了兴奋性神经毒性，导致神经元死亡。
The abnormal metabolism and excess release of Glutamic acid as well as high-frequency stimulation to the postsynaptic receptor induce excitatory neural toxicity, resulting in the death of neurons.
结果：神经胶质瘤细胞株u343表达死亡受体DR5, DR 5分布于细胞内细胞核的周围。
Results: The expression of death receptor 5 (DR5) was certificated in U343, DR5 appeared to be located in intracellular perinuclear compartment.
免疫组化和流式细胞术检测肾脏TRAIL基因及其死亡受体DR 4、DR5的蛋白表达。
Immunohistochemistry and FCM were used to detect the expression of TRAIL and its death receptors (DR4 and DR5).
目的：构建人死亡受体5 (DR5)真核表达载体，转染NS - 1细胞，建立稳定转染的NS - 1细胞系。
Objective: to construct eukaryotic expression vector of human death receptor (DR5) and transfect NS-1 cells to establish stable NS-1 cell line.
死亡受体在胰腺癌中高表达，可能在TRAIL诱导胰腺癌细胞凋亡的机制中发挥重要的作用。
High death receptor expression may play an important role in TRAIL inducing pancreatic carcinoma apoptosis.
目的探讨死亡受体dr5在急性非淋巴细胞白血病(ANL L)细胞中的表达及其临床意义。
AIM to reveal the expression of death receptor 5 (DR5) in the cells of acute non lymphocyte leukemia (ANLL) and its clinical significance.
结论：苦参碱能诱导C6胶质瘤细胞的凋亡，其机制与死亡受体途径和线粒体途径的众多基因有关。
Conclusion: Matrine can induce C6 glioma cell apoptosis and the mechanism might be related to a number of genes involved in death receptor pathway and mitochondrial pathway.
死亡受体通过细胞内信号传导途径可诱导细胞凋亡，与机体的生长、发育、病变和死亡有关。
Death receptors induce apoptosis by intracellular signaling transmission and relate to body growth, development, disease and death.
本文提供了反转或阻止靶细胞对死亡受体激动剂的抗性的方法。
Provided herein is a method of reversing or preventing a target cell's resistance to a death receptor agonist.
我们的结果还进一步表明PD-1／PD-L1途径对T淋巴细胞凋亡的影响是同时通过内源性死亡受体途径和外源性死亡受体途径产生的。
Our results further showed that the PD-1/PD-L1 pathway which could reduce the rate of T lymphocyte apoptosis via the death receptor pathway of endogenous and exogenous death receptor pathway.
目的探讨死亡受体5 (DR5)对神经细胞增殖的影响。
Objective to investigate the influence of death receptor 5 (DR5) in the proliferation of nerve cells.
和活体同种异体移植受体相比，死亡供体同种异体受体的疗效较差。
Deceased donor allograft recipients have worse outcomes compared with living allograft recipients.
和活体同种异体移植受体相比，死亡供体同种异体受体的疗效较差。
Deceased donor allograft recipients have worse outcomes compared with living allograft recipients.
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