• 生发中心树突状细胞可以内吞这种抗原物质将其呈递给T 细胞从而激活它们

    Dendritic cells in the germinal center may endocytose such antigenic material and present it to T cells, activating them.

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  • 结果脾脏扁桃体树突状细胞胞浆能够CR 2抗体强烈染色

    RESULTS: the follicular dendritic cells (FDC) in the spleen and tonsil tissues were intensely stained by CR2 antibodies.

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  • 组蛋白去乙酰酶抑制剂降低抗原提小鼠骨髓来源树突状细胞活性

    Histone deacetylase inhibitors decrease the antigen presenting activity of murine bone marrow derived dendritic cells.

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  • 这些树突状细胞具有巨噬细胞表型特征包括强烈HLA-DR表达

    This highly dendritic cell of the dermis possesses phenotypic characteristics of macrophages, including strong HLA-DR expression.

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  • 正常树突状细胞会把异源体递T细胞使其产生杀伤性T淋巴细胞摧毁

    Normally dendritic cells show an invader to T cells which produce cytotoxic T cells to destroy it.

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  • 使用大量树突状细胞,和对照组小鼠相比肿瘤生长抑制效果达到41%。

    When large numbers of DCs were used, tumor growth was suppressed up to 41% when compared to control mice.

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  • SOCS1沉默树突状细胞能够促进自身成熟增强其诱导T细胞肿瘤活性。

    SOCS1 silent DC could promote DC maturity and enhance the antitumor response of t cell.

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  • 抗原刺激树突状细胞免疫调节功能肿瘤患者慢性病毒感染动物模型已有报道

    The immune modulator capacity of antigen-pulsed dendritic cells (DC) has been documented in patients with cancers and in animal models of chronic viral infections.

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  • 结论骨髓间充质细胞上清可抑制单核细胞来源树突状细胞成熟功能诱导免疫耐受

    Conclusion Human bone marrow mesenchymal stem cells inhibit maturation and function of monocyte-derived dendritic cells and induce immune tolerance.

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  • 形成对照是,容易形成艾滋病人类恒河树突状细胞容易HIV和SIV激活。

    In contrast, the easy form of human AIDS and rhesus monkeys dendritic cells can easily be activated HIV and SIV.

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  • 探讨致敏树突状细胞(DC)激活肿瘤浸润淋巴细胞TIL体外小鼠乳腺癌活性。

    Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.

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  • 单用DNA疫苗联用TLR免疫树突状细胞表面共刺激分子表达水平没有统计学上显著差异

    No statistically significant difference in the expression levels of co-stimulatory molecules on dendritic cells surface between the groups immunized with DNA vaccine alone or with TLRs.

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  • 探讨肿瘤多肽致敏白介素12 (IL 12 )基因修饰树突状细胞DC)对自发性转移治疗作用。

    Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).

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  • :应用黑色素瘤基因(MAGE-1)多肽负载的树突状细胞DC体外诱导出高度特异性肝癌免疫应答

    Objective: To induce efficient and specific anti-human hepatocellular carcinoma(HCC) immunological response in vitro by DC pulsed with MAGE-1 nonapeptide.

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  • 方法:根据细胞黏附性不同建立一整套简便的树突状细胞体外扩增方法利用HE染色FACS研究了生物学特征

    Methods According to the difference of cells s adhesion, a series of method were set up to generate DC and the biological characteristics were studied by he staining and FACS.

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  • 探讨负载肿瘤抗原树突状细胞(DC)疫苗诱导细胞毒性T淋巴细胞(CTL)体外杀瘤作用及对荷瘤小鼠治疗作用。

    Objective: to explore the anti-tumor effects of cytotoxic of T-lymphocytes (CTL) induced by dendritic cells (DC) vaccine loaded with tumor antigen.

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  • :探讨改善外周血来源树突状细胞DC体外培养方法促进DC成熟提高其递呈抗原激发特异性免疫反应能力。

    PART I The Improvement of Dendritic Cell Culture Measures in vitroObjective: Improve the measures of dendritic cell culture in vitro, to increase the rate of mature and function of DC.

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  • 结果表明:乳腺癌组织中散分布S100蛋白阳性树突状细胞,而癌周癌旁淋巴细胞细胞密集区可见树突状细胞存在。

    The result showed that S100 protein positive dendritic cells distributed sparsely in malignant cells and formed a cluster among lymph cells and plasma cells.

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  • 探讨动员人外周造血细胞体外培养扩增获得树突状细胞(DC)生物学特性,为临床应用肿瘤树突状细胞疫苗建立制备方法

    Objective to obtain dendritic cells (DCs) from peripheral blood stem cells and hematopoietic precursor cells in vitro, and assess the feasibility of clinical application of tumor vaccine.

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  • 结论得到较高程度表达CD 83、CD 86HLA - DR分子体外可强烈激发同种异体t淋巴细胞增殖树突状细胞群。

    CONCLUSION: a group of dendritic cells, which highly express CD83, CD86 and HLA-DR molecules, and stimulate strongly allogeneic t lymphocyte proliferation in vitro, are obtained.

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  • 探讨细胞介素23 (IL - 23)基因转染树突状细胞(DC)负载凋亡细胞抗原后诱导免疫应答小鼠胰腺癌治疗作用

    Objective to investigate the therapeutic effects on pancreatic carcinoma by dendritic cells (DCs) transfected with interleukin (IL) -23 and acquiring apoptotic cell antigen.

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  • 研究小鼠骨髓细胞体外诱导分化树突状细胞T细胞增殖影响进一步研究树突状细胞功能及临床肿瘤治疗提供有效实验方法

    Objective To study the effects of mature dendritic cells (DCs) derived from mouse bone marrow on T cell proliferation in vitro, and provide techinological methods for tumor therapy.

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  • 观察体外构建榄香烯复合瘤苗抗原-卡介苗休克蛋白70复合物(HTA-HSP70BCG诱导 树突状细胞疫苗 肿瘤效应

    Objective To investigate antitumor effects induced by dendritic cells (DCs) pulsed with complex of tumor antigen from elemene-combo tumor cell vaccine-heat shock protein 70 of BCG (HTA-HSP70BCG).

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  • 方法根据不同时期树突状细胞粘附性质不同,设计简便的树突状细胞体外扩增纯化方法利用瑞氏染色流式细胞仪(FACS鉴定生物学特征

    Methods According to different adhesiveness of DC in vary period, a simple method was used to generate and purificate DC, and their biology character were identified by Wright staining and FACS.

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  • 1973年,发现树突状细胞这种细胞因为伸出类似神经细胞树突突起而得名,这种结构也它们功能有关

    In 1973, he discovered the dendritic cell - so named because it has little tails, like dendrites in neurons - and set about explaining their function.

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  • 斯坦证明树突状细胞可激活T细胞——适应性免疫反应中发挥重要作用一类细胞

    Steinman proved that dendritic cells activate t cells, a class of white blood cells that are important in adaptive immunity.

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  • 探讨胸腺树突状细胞分布数量不同种属关系

    Objective To study the relationship between quantity and distribution of thymus dendritic cells in various species.

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  • 观察小鼠胸腺树突状细胞(TDC)形态

    Objective To observe the morphology of mouse thymic dendritic cells (TDC).

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  • 梭形细胞黑色素瘤指状突树突细胞肉瘤:它们代表相同过程吗?

    Spindle Cell Melanoma and Interdigitating Dendritic Cell Sarcoma: Do They Represent the Same Process?

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  • 青藤碱类风湿作用可能与其抑制树突状细胞分泌细胞介素12有关

    The therapeutic effect of sinomenine on rheumatoid arthritis may be related to its inhibition to secretion of IL-12 in DCs.

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