该小组目前正在肝癌动物模型中验证LSF的小分子抑制剂，作为可能的治疗方法。
The team is currently testing small molecule inhibitors of LSF as a possible therapy for HCC in animal models.
介绍了最近几年来关于酪氨酸蛋白磷酸酯酶1B作用的机制以及通过各种途径发现的结构新颖的小分子抑制剂的构效关系研究进展。
The advances made in the new compounds identified as Protein Tyrosine Phosphatases 1B (PTP1B) inhibitors recently and their structure-activity relationship were reviewed in this paper.
据彼得森，小分子抑制剂如ipa - 3等，是很有希望的发现药物的工具。
According to Peterson, small molecule inhibitors such as IPA-3, are promising tools for drug discovery.
KRAS基因突变在恶性肿瘤组织中频发，可预测非小细胞肺癌分子靶向治疗的疗效和预后，针对RAS基因的分子抑制剂研究仍处于初级阶段。
KRAS mutation frequency in tumor tissue, can be predicted non-small cell lung cancer molecular targeted therapy efficacy and prognosis, and molecular inhibitors of RAS genes is still in its infancy.
研究了不同结构的小分子有机抑制剂对脆硫锑铅矿和铁闪锌矿可浮性的影响。
The effect of small molecule organic depressors of various structures on the floatability of jamesonite and christophite was studied.
单克隆抗体和小分子抑制剂常常互补并且是比较成功的用于临床的方法。
Of these, monoclonal antibodies and small-molecule inhibitors have been the more successful, and often complementary, approaches so far in clinical Settings.
考察柠檬酸等有机小分子抑制剂和其他无机调整剂对锂辉石与绿柱石的抑制作用。
The influence of low molecular organic depressants such as citric acid on the floatability of spodumene and beryl, as well as inorganic modifiers has been studied through flotation tests.
设计并合成了一种可以抑制硫化矿的小分子有机抑制剂甘油基黄原酸钠，通过浮选试验考察了该抑制剂对硫化矿物的浮选抑制行为。
A small molecular organic depressant, glyceryl-xanthate sodium, was designed and synthesized, and its behavior in depressing sulfide minerals was investigated by flotation tests.
第二章共分为三节：第一节就联苯取代的1，2，4-恶二唑类小分子PKB抑制剂的设计进行了介绍。
In the first section, the design of the 1,2,4-oxadiazole containing biphenyl structure class of small molecule PKB inhibitors were introduced.
小分子酪氨酸激酶抑制剂为治疗EMS带来新的希望。
The small molecule tyrosine kinase inhibitors may bring hope in the future for patient with EMS.
随着小分子酪氨酸激酶抑制剂在非小细胞肺癌治疗上获得成功，陆续有其治疗非小细胞肺癌脑转移及脑膜转移的研究。
With the success of small-molecule tyrosine kinase inhibitors in non-small cell lung cancer, recent clinical researches have shown their activities against brain and leptomeningeal metastases.
本文就小分子酪氨酸激酶抑制剂治疗非小细胞肺癌脑转移的机理、临床应用以及治疗失败后的处理等方面作一综述。
The mechanisms, clinical applications of small-molecule tyrosine kinase inhibitors on brain metastasis and therapeutic choice after the failure will be reviewed in this article.
该文重点介绍近年来报道的不同结构类型的小分子端粒酶抑制剂，并对其活性及构效关系进行综述。
This review had highlighted recent developments in different chemical types of telomerase inhibitors. The biological activity and the structure-activity relationship aspects were also described.
该文重点介绍近年来报道的不同结构类型的小分子端粒酶抑制剂，并对其活性及构效关系进行综述。
This review had highlighted recent developments in different chemical types of telomerase inhibitors. The biological activity and the structure-activity relationship aspects were also described.
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