目的:研究自发性高血压大鼠(SHR)左心室肌细胞动作电位时程延长的膜离子流基础。
Objective: To study the membrane ionic basis of action potential prolongation of hypertrophied left ventricular myocytes in spontaneously hypertensive rats (SHR ).
方法应用全细胞膜片钳技术记录乌头碱对大鼠心肌细胞动作电位时程的作用,分别给予奎尼丁、维拉·帕米处理比较二者对动作电位时程的影响。
Methods Effects of quinidine and verapamil on the alteration of action potential duration induced by aconitine were studied by use of the whole cell patch clamp techniques in rat ventricular myocytes.
结果:心衰康煎液可以明显延长刺激引起动作电位的潜伏期及明显缩短动作电位时程。
Results: Xinshuaikang decoction could prolong the latent period of AP induced by electrical stimulation and shorten the APD Jignificantly.
结果:心衰康煎液可以明显延长刺激引起动作电位的潜伏期及明显缩短动作电位时程。
Results: Xinshuaikang decoction could prolong the latent period of AP induced by electrical stimulation and shorten the APD Jignificantly.
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