骨髓来源的内皮祖细胞改善内皮功能,并且能预测心血管风险。
Bone marrow-derived endothelial progenitor cells (EPC) improve vascular function and predict cardiovascular risk.
这使得他们能够区分骨髓来源的内皮祖细胞和其他组织来源的内皮细胞。
This enabled them to differentiate EPCs that originated in the bone marrow from endothelial cells that are found in normal tissues throughout the body.
部分移植的内皮祖细胞特定定位接近于血管营养神经,而少部分内皮祖细胞与内皮细胞一起存在。
A portion of engrafted EPCs were uniquely localized in close proximity to vasa nervorum, and a smaller portion of these EPCs were colocalized with endothelial cells.
流式细胞分析显示神经生长因子处理后能够增加C57BL/6小鼠外周循环系统中的内皮祖细胞数量急剧增加。
Flow cytometric analysis revealed that NGF treatment increased the number of EPCs in the peripheral circulation of C57BL/6 mice.
Adams说未来的研究将观察循环中的内皮祖细胞水平多长时间能够降到正常水平,以及暂时的内皮祖细胞水平下降是否对心脏和内皮功能产生影响。
Adams said further studies were underway to see how long it takes to normalise circulating progenitor cell levels, and whether the temporary decrease has any impact on heart and endothelial function.
恢复的机制可能是激发了自体的血管生成的级联反应,内皮祖细胞不仅促进新生血管的形成,并且加速它们的成熟和稳定。
It is likely that restoration of the angiogenic cascade by autologous EPCs involved not only generation of new vessels but also acceleration of their maturation and stabilization.
我们同样检测来源于骨髓的循环祖细胞的CD 34 +CD 133 +丛族数量,作为血管再生和内皮活动能力指数。
We also quantified the CD34 + CD133 + population of circulating progenitor cells (CPCs) that originate from bone marrow, as an index of hematopoietic and endothelial mobilization capacity.
目的:拟建立从紫绀型先天性心脏病患儿外周血获取内皮祖细胞的方法。
OBJECTIVE: to establish methods of harvesting endothelial progenitor cells from peripheral blood in children patients with cyanotic congenital heart disease.
循环内皮细胞的数量与年龄、循环祖细胞的数量没有关系。
背景动物实验数据表明,内皮祖细胞移植能减轻野百合碱所致的大鼠和狗的肺动脉高压。
Background Experimental data suggest that transplantation of EPCs attenuates monocrotaline-induced pulmonary hypertension in rats and dogs.
本研究探讨骨髓内皮细胞分泌的造血抑制因子在扩增造血祖细胞中的作用并初步探讨其作用机制。
In this study, the roles of hematopoietic inhibitors elaborated by bone marrow endothelial cells in the proliferation and differentiation of hematopoietic progenitors were investigated.
目的探讨环氧化酶(COX)1、2在缺血心肌血管生成和内皮祖细胞动员中的作用及机制。
Objective To investigate the effect of COX1 and COX2 on angiogenesis and endothelial progenitor cell mobilization in rats with experimental myocardial infarction(MI).
结论:体外扩增法成功地从兔骨髓中分离培养出具有血管内皮祖细胞特征的细胞群体。
CONCLUSION: Cell colony with the feature of EPCs can be isolated and cultured from rabbit bone marrow by in vitro amplification method successfully.
目的研究外周血来源内皮祖细胞的分离、培养、分化及鉴定方法。
Objective to study the methods of isolation, culture, differentiation and identification of endothelial progenitor cells (EPC) from peripheral blood.
内皮祖细胞被认为是有修复破损内皮细胞和提高内皮功能和灌注的功能。
Endothelial progenitor cells are thought to have the capacity to repair damaged endothelium and improve endothelial function and perfusion.
计数结果显示,随着加入雌激素浓度的增加,各组内皮祖细胞数量差异具有显著性意义(P<0.05)。
The results of counting showed that with the increase of concentration of oestrogen, there was significant difference of the number of EPCs in each group (P< 0.05).
探讨内皮祖细胞修复动脉内皮损伤的作用。
To investigate the reparative functions of endothelial progenitor cells (EPCs) transplantation in the arterial endothelium injury.
这些结果为内皮祖细胞(EPC)的募集的机制提供新的视角,同时为阻止病理性血管发生的新方法提供依据。
Thus, our results provide new insights into the mechanisms underlying EPC recruitment and the bases for novel strategies to hinder pathological angiogenesis.
现主要综述内皮祖细胞在心血管疾病中的应用及存在问题。
This paper reviews the application and potential problems with therapeutic use of EPCs in cardiovascular diseases.
血管内皮祖细胞是一类能循环、增殖并能直接分化为血管内皮细胞的前体细胞。
Endothelial progenitor cell (EPC) is a subtype of progenitor cells that can circulate, proliferate and have the ability to differentiate into mature endothelial cells.
目的观察不同浓度白藜芦醇对于内皮祖细胞体外功能的影响。
AIM to investigate the effect of resveratrol on the function of endothelial progenitor cells (EPCs).
目的观察血管内皮生长因子受体1 (VEGFR1)阳性造血祖细胞与人大肠癌转移的关系及机制。
Objective to investigate the relation of vascular endothelial growth factor receptor 1 (VEGFR1) -positive hematopoietic progenitor cell with the metastasis of human colorectal carcinoma.
近年的研究认为,内皮祖细胞参与血管内皮损伤后的修复。
Recent researches demonstrated that endothelial progenitor cells play an important role in repair of injured endothelium.
内皮祖细胞来源于骨髓,可分化为成熟有功能的内皮细胞。
Endothelial progenitor cells (EPC) are bone marrow derived cells with the potential to differentiate into mature functional endothelial cells.
目的观察趋化因子sdf- 1促内皮祖细胞增殖、迁移和管型形成的作用。
Objective to explore the effect of chemokine SDF-1 on the proliferation, migration and in vitro of human endothelial progenitor cells (EPCs).
事实上,经过第一阶段的身体锻炼,这些患者血中内皮祖细胞数目增多。
After the first physical sessions, in fact, the blood of these patients showed an increased number of endothelial progenitor cells.
目的研究内皮祖细胞(EPC)的分离、培养、分化及鉴定。
Objective To investigate the methods of isolating, culturing, differentiating and evaluating the endothelial progenitor cell (EPC ) .
内皮祖细胞的动员和其介导的血管新生受到精细的调节。
Mobilization and endothelial progenitor cell-mediated neovascularization is critically regulated.
作者认为,“结果提示,肿瘤的高度进展性与内皮祖细胞循环高水平之间可能存在某种关联性”。
"These findings could suggest a possible relationship between more aggressive tumor and higher circulating levels of EPCs, " the authors state.
注射内皮祖细胞有词望成为治疗心脑血管病的一种新手段。
The injection of endothelial progenitor cells is promising to become a novel approach for the treatment of cardio-cerebrovascular diseases.
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