目的研究白蛋白纳米粒的去溶剂化法制备工艺。
OBJECTIVE To optimize the preparation method of albumin nanoparticles by desolvation.
结论优化了叶酸偶联米托蒽醌白蛋白纳米粒的制备工艺。
CONCLUSION The preparation method of MTO-BSANP-folate was optimized.
目的研究能通过叶酸受体介导靶向肿瘤细胞的叶酸偶联白蛋白纳米粒。
Objective: to study folate-conjugated albumin nanoparticles targeting to tumor cells via folate receptor-mediated endocytosis.
摘要目的研究能通过叶酸受体介导靶向肿瘤细胞的叶酸偶联白蛋白纳米粒。
Objective: to study folate -conjugated albumin nanoparticles targeting to tumor cells via folate receptor-mediated endocytosis.
结论外置定位磁场下，经动脉途径注入磁性白蛋白纳米粒的磁靶向化疗栓塞效果最好。
Conclusions: the administration of albumin nanoparticles via hepatic artery under guidance of an external magnetic field was the most effective way for hepatocarcinoma therapy of rat.
结果显示：外置磁场能使磁性白蛋白纳米粒在靶区定位聚集，并减少其在非靶区的分布；
Results:1. Under the infuence of magnetic field, ANP can deposit in the target area at large degree, as a result, the density of ANP in the nontarget area can be decreased significantly;
目的观察磁性阿霉素白蛋白纳米粒在移植性肝癌模型中的磁靶向性，并观察磁性白蛋白纳米粒在各脏器中的分布特征。
Objective to investigate the effect of magnetic field application to target distribution of the nanoparticles in the model of transplanted liver cancer in rats.
用圆二色光谱，紫外-可见光谱研究银纳米粒子与血清白蛋白的相互作用及其相关效应。
Interraction and correlation effect of silver nanoparticles and serum albumin were reached by circular dichroism spectrum.
因此，静脉注射半乳糖化白蛋白阿霉素磁性纳米粒是可行的。
So it was feasible that adriamycin contained by galactosed magnetic albumin nanoparticle was administrated intravenously.
因此，静脉注射半乳糖化白蛋白阿霉素磁性纳米粒是可行的。
So it was feasible that adriamycin contained by galactosed magnetic albumin nanoparticle was administrated intravenously.
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