目的观察供体白细胞输注(DL I)治疗急慢性白血病和多发性骨髓瘤的疗效和安全性。
Objective To observe the therapeutic efficacy and safety of donor leukocyte infusion (DLI) in acute, chronic leukemia and multiple myeloma.
对于服用抗生素或抗真菌药物而无起色的严重的细菌或真菌感染病例通常采取白细胞输注的方法。
White cell transfusion is usually reserved for uncommon instances of severe infections with bacteria or fungi that do not respond to antibiotics or anti-fungal drugs.
结论:(1)供者白细胞的输注能使某些BMT后慢性粒细胞性白血病遗传学及血液学复发患者完全缓解。
Conclusion: (1) Donor derived leukocyte infusion can induce CML post BMT to cytogenetic and hematological CR. It has also therapeutic effects on acute leukemia relapse but is less sustained.
在输注之前应先滤去除捐献血小板中的白细胞,如果有必要,这些血小板还应经过辐照处理。
Donated platelet units should have the white cells removed by filtration prior to transfusion and, if appropriate, should be irradiated as well.
输注血小板的量和白细胞恢复时间,ABO相合与不合者无明显差异。
The time for stem cell engraftment and the platelet concentrates transfusions were not significantly different between patients undergoing ABO compatible and incompatible transplantation.
另一种可选疗法是二次移植,就是对患者施以供体淋巴细胞输注(即注入的白细胞为来自原造血干细胞供体的淋巴细胞)。
Many CML patients cannot have an allogeneic stem cell transplant. Doctors are studying the use of a patient's own stem cells in these cases. This is called an autologous stem cell infusion .
在其它临床状况下(如外科手术),滤除输注血液成分中的白细胞,能在很大程度上预防输血引起的不良免疫效应。
In other clinical Settings (surgery) filtering out white cells from transfusion components appears to prevent deleterious immune effects of transfusion to a large degree.
但是,保存前白细胞滤除更有利于红细胞悬液的保存和输注安全,更适合临床尤其是白血病患者使用。
But it is beneficial to RBC preservation and transfusion safety, and more suitable for clinical use especially patient who suffer from leukemia.
但是,保存前白细胞滤除更有利于红细胞悬液的保存和输注安全,更适合临床尤其是白血病患者使用。
But it is beneficial to RBC preservation and transfusion safety, and more suitable for clinical use especially patient who suffer from leukemia.
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