内源性血管生成抑制剂可作为一种抑癌蛋白。
Endogenous angiogenesis inhibitors act as tumor suppressor proteins.
目的通过检测肿瘤抑制基因产物pten蛋白在肝癌中的表达情况,探讨其作为一种评估肝细胞癌(HCC)生物学特征的分子标记的意义。
Objective to detect the expression of PTEN protein in hepatocellular carcinoma (HCC) to determine whether it can be used as a new molecular label for evaluation of biological characteristics of HCC.
目的:了解金属蛋白酶组织抑制因子- 1在食管癌中的作用。
Purpose: to investigate tissue inhibitor of metalloprotEinase-1 (TIMP1) gene expression in patients with carcinoma of esophagus.
目的:探讨X染色体相关的凋亡抑制蛋白在肾细胞癌中的表达及其与细胞凋亡的关系。
Objective: to study expression of XIAP and its relationship to apoptosis in renal cell cancer.
FBW7是一种肿瘤抑制蛋白,其基因在多种肿瘤包括直肠癌、胃癌、卵巢癌和白血病中存在着基因突变或缺失。
FBW7 is a tumor suppressor, and its gene is frequently mutated or deleted in various human cancers including colorectal, gastric, ovarian and leukemias.
组蛋白脱乙酰基酶抑制剂已被证实具有抗肿瘤作用,多种有关组蛋白脱乙酰基酶抑制剂的药物临床试验正在进行中,以期成为治疗宫颈癌的一个新方向。
HDI has been proved to have antitumor activities and a number of clinical trials relating to HDI are in progress. It is expected that HDI becomes a new therapy of cervical cancer.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
抑癌蛋白p53通过调节下游靶基因的转录,参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
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