虽然许多原癌基因和肿瘤抑制基因被广泛表达，这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
BRMS1是2000年在乳腺癌细胞中发现的癌转移抑制基因。
BRMS1 is a tumor metastasis suppressor gene discovered in breast carcinoma cells in 2000.
癌转移抑制基因是一类只抑制癌细胞的转移而不影响肿瘤的发生与生长的基因。
Tumor metastasis suppressor gene is a kind of genes that only suppresses metastasis without affecting tumorigenicity and tumor growth.
结果人血管抑素基因可明显的抑制卵巢癌裸鼠移植瘤生长。
Results Human angiostatin gene could suppress the growth of transplanted tumor from ovarian neoplasm nude mice obviously.
方法建立人卵巢癌裸鼠动物模型，检测腺病毒介导的人血管抑素基因对肿瘤生长的抑制作用。
Methods A human ovarian cancer model using a nude mice was built to test the suppressive effect of human angiostatin gene mediated by adenovirus on the tumor growth.
目的：探讨重组慢病毒介导的体外转导OPCML基因的可行性及其对卯巢上皮性癌（卵巢癌）细胞的抑制作用。
Objective: To study the inhibition of OPCML to ovarian cancer cell lines using a lentiviral vector system for efficient gene transduction.
目的通过检测肿瘤抑制基因产物pten蛋白在肝癌中的表达情况，探讨其作为一种评估肝细胞癌(HCC)生物学特征的分子标记的意义。
Objective to detect the expression of PTEN protein in hepatocellular carcinoma (HCC) to determine whether it can be used as a new molecular label for evaluation of biological characteristics of HCC.
通过裸鼠致癌实验，观察了E1 A基因对裸鼠移植癌生长的抑制作用。
The growth inhibition of E1A gene on the transplantation tumor in nude mice was observed by the experiment of carcinogenesis in nude mice.
中医药在抑制血管生成、促进细胞凋亡、调节内分泌系统和抑制癌基因表达方面对癌前病变的干预作用。
Traditional Chinese medicine (TCM) has shown effects on precancerous changes through inhibiting angiogenesis, promoting apoptosis, modulating endocrine system and restraining oncogene expression.
抑癌蛋白p53通过调节下游靶基因的转录，参与细胞凋亡、细胞周期抑制、DNA损伤修复等多种生物学过程。
The tumor suppressor p53 regulates cell cycle arrest, apoptosis and DNA repair processes by controlling various target genes that contain p53 sequence-specific DNA binding sites.
FBW7是一种肿瘤抑制蛋白，其基因在多种肿瘤包括直肠癌、胃癌、卵巢癌和白血病中存在着基因突变或缺失。
FBW7 is a tumor suppressor, and its gene is frequently mutated or deleted in various human cancers including colorectal, gastric, ovarian and leukemias.
FBW7是一种肿瘤抑制蛋白，其基因在多种肿瘤包括直肠癌、胃癌、卵巢癌和白血病中存在着基因突变或缺失。
FBW7 is a tumor suppressor, and its gene is frequently mutated or deleted in various human cancers including colorectal, gastric, ovarian and leukemias.
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