目的研究瘦素和瘦素受体在肺癌组织中的表达。
Objective to study the expression of leptin and leptin receptor in lung carcinoma.
瘦素受体的表达与瘦素表达明显相关（P<0.01）。
The expression of OB-R showed a significant correlation with the level of leptin expression (P< 0.01).
目的探讨血清瘦素水平，瘦素受体变异与乳腺癌发生的关系。
Objective To explore the relations between blood LEP level, LEP receptor variation and breast cancer.
目的观察胎儿腮腺内瘦素和瘦素受体的表达、分布及发育规律。
Objective to study the expression, distribution and development regularity of leptin and its receptor in the fetal parotid gland.
的观察胎儿舌下腺内瘦素和瘦素受体的表达、分布及发育规律。
Objective to study the expression, distribution and the development regularity of leptin and its receptor in the fetal sublingual glands.
结论血清瘦素水平高，瘦素受体变异为乳腺癌发生的可疑危险因素。
Conclusion the high blood LEP level and the mutation of the LEP receptor may be risk factors of breast cancer.
结论：瘦素受体基因外显子4中519位点变异不是肥胖症的遗传因素。
CONCLUSION: Variation of exon 4 in LEPR gene at site 519 is not a genetic factor of obesity.
结果：研究表明瘦素和瘦素受体与高血压心肌肥厚的发病机制有密切关系。
Results: Research indicated that Leptin and Leptin receptor (OB-Rb) was closely related to the pathogenesis of Hypertensive Cardiac Myocyte Hypertrophy.
结论糖尿病大鼠心脏成纤维细胞短型瘦素受体表达增加与心脏纤维化并存。
Conclusions The coexistence of cardiac fibrosis and increased expression of Ob-Ra mRNA in myocardial fibroblasts were found in diabetic rats.
目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
Objective to investigate effects of leptin on gene and protein expression and tyrosine phosphorylation of leptin receptor in rat hepatocytes.
目的观察瘦素对大鼠肝细胞瘦素受体蛋白、基因表达及酪氨酸磷酸化的影响。
The role of adhesion moleculesinduced tyrosine phosphorylation proteins in procollagen expression in fibroblasts;
瘦素作为脂肪组织分泌的肽类激素，与瘦素受体结合后发挥调节体质量的作用。
As a kind of peptide hormone secreted by fatty tissue, leptin play its role in regulating body weight by combining with leptin receptor.
结论胎儿腮腺内有瘦素和瘦素受体表达，可能参与调节胎儿腮腺和胃肠的发育及功能活动。
Conclusion Leptin and its receptor was present in fetal parotid gland, which may be involved in the fetal parotid gland and gastrointestinal development and the functional regulation.
一次性游泳运动能够提高大鼠下丘脑瘦素受体的表达，运动可能促进血瘦素向下丘脑转运。
Acute aerobic exercise can up-regulate the expression of leptin-receptor in hypothalamus of rats, and exercise may promote the transportation of leptin from blood to cerebrospinal fluid.
如果我们能够研发出“更聪明的药物”，比如瘦素受体激动剂，那么它肯定有巨大的治疗潜力。
If you could get a clever leptin agonist molecule then there is of course huge potential for the treatment.
目的探讨血瘦素水平和瘦素受体（LR）基因多态性对胰岛素敏感性影响及与缺血性脑血管病发病的关联。
Objective To study the effects of plasma leptin level and leptin receptor(LR) gene polymorphism on the insulin sensitivity and their relation to ischemic stroke.
实验研究的小鼠缺乏瘦素与脑内的瘦素受体，瘦素是一种参与机体许多生理功能的激素，包括调节食欲和新陈代谢。
The mice in the study lacked leptin and receptors in the brain for leptin, a hormone that is involved with many bodily functions, including regulating appetite and metabolism.
结论单纯型肥胖儿童瘦素受体基因第20外显子存在基因多态性的变化，且这种变化明显影响肥胖儿童的脂质代谢及体脂分布。
Conclusion There is polymorphism at 20 exon LEPR gene in children with obesity, which may affect the lipid metabolism and the fat distribution.
新研究中，研究人员通过使老鼠只在促性腺激素中缺少胰岛素受体进行观察。当瘦且健康时，那些老鼠表现的很好。
In the new study, the researchers investigated by creating mice lacking insulin receptors only in the gonadotroph. When healthy and lean, those mice appeared to do just fine.
目的：确定瘦素及其功能受体在脱出间盘组织中的表达，阐明瘦素是否能促进鼠np细胞在体外的增殖。
Objective. To determine the expression of leptin and its functional receptor in herniated disc tissues, and to elucidate whether leptin can stimulate rat NP cells to proliferate in vitro.
结论瘦素可能通过受体系统，与生殖器官间有广泛联系，影响女性的生殖功能。
Conclusion leptin may have an effect on women's reproductive function through leptin receptor systems.
目的探讨瘦素及其受体在椎间盘组织表达及意义。
Objective to study the expressions and their significance of leptin and leptin receptor in intervertebral disc.
瘦素是肥胖基因的表达产物，通过与其受体结合发挥其生物学作用。
The leptin is a expression product of the obesity gene. Biological effect of leptin-has appeared by combination with its receptor just.
本文综述了瘦素及其受体的结构和特征、瘦素的主要生理功能及其在细胞中的信号转导途径。
This review is about the structures and characteristics of leptin and its receptor, main physiological functions and signal transduction pathway in cells.
本文综述了瘦素及其受体的结构和特征、瘦素的主要生理功能及其在细胞中的信号转导途径。
This review is about the structures and characteristics of leptin and its receptor, main physiological functions and signal transduction pathway in cells.
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