BRD7基因是与鼻咽癌相关的候选抑瘤基因。
BRD7 gene is a novel candidate tumor suppression gene associated with NPC.
目的瘤基因(WT1)突变与白血病发病的关系。
Objective To analyze mutations in the Wilms tumor gene (WT1) in Ieukemogenesis.
结论：EGFR有可能成为胶质瘤基因治疗的候选基因。
Conclusion: It is possible to use EGFR as a candidate gene for gene therapy of malignant gliomas.
干细胞具有向恶性胶质瘤趋向性迁移的特性，并可能成为恶性胶质瘤基因治疗的理想载体。
Various studies have demonstrated the tremendous tropism of stem cells for malignant gliomas, making these cells a potential vehicle for delivery of therapeutic genes to disseminated glioma cells.
方法获取10例淋巴瘤患者的活检淋巴结组织，以CGH技术检测淋巴瘤基因组d NA拷贝数的变化。
Methods Biopsy specimens of lymph nodes were obtained from 10 cases of lymphoma patients. The changes of DNA copies number (e. g. deletion and amplification) were detected using the CGH technique.
目的：应用黑色素瘤基因（MAGE-1）多肽负载的树突状细胞（DC）在体外诱导出高度特异性的抗肝癌免疫应答。
Objective: To induce efficient and specific anti-human hepatocellular carcinoma(HCC) immunological response in vitro by DC pulsed with MAGE-1 nonapeptide.
本研究基于自组织映射网络(SOM)，分析多骨髓瘤基因表达数据，建立预测多骨髓瘤的自组织预测模型(SOPM)。
Multiple myeloma gene expression data was analyzed and Self Organization Prediction Model (SOPM) based on Self-Organization Mapping (SOM) networks was established for predicting multiple myeloma.
结论FHIT和WWOX基因系重要的候选抑瘤基因，与其他预后指标的联合检测可望对患者的治疗预后作出更准确的预测。
Conclusions FHIT and WWOX are candidate tumor suppressor genes. Detected coordinately with other (molecular) parameters, they can make the prognosis of therapy more accurate to predict.
异常的超变和异常的致癌基因 BCL-6与淋巴瘤的发生具有相关性。
Aberrant somatic hypermutation and deregulation of the oncogene BCL-6 are associated with lymphomagenesis.
将近半数的黑色素瘤患者都有BRAF基因突变，从而导致黑色素肿瘤细胞继续生长。
About half of all melanoma patients have a mutated BRAF gene. This mutation tells the cell to continue to grow.
在实验室，他们用病毒感染那些细胞，这种病毒携带有能产生T细胞受体的基因，在这个例子中，实质上就是产生黑色素瘤导归器的基因。
In the lab, they infected those cells with a virus carrying genes that create T-cell receptors, essentially homing devices for, in this case, melanoma.
研究人员用一段被他们进行基因编码的基因重组病毒感染T细胞，这段基因编码是能够识别黑色素瘤细胞的受体蛋白的。
They did this by infecting the T-cells with genetically modified viruses carrying genes that coded for receptors to melanoma molecules.
罗氏公司的vemurafenib通过阻断一种突变的基因b - raf攻击晚期黑色素瘤。
Roche's vemurafenib attacks advanced melanoma by blocking the mutated form of a gene, B-RAF.
Plexxikon之所以能开发出这种药物，是因为研究人员利用基因测序仪绘出了黑色素瘤细胞的基因组，并发现了一个关键的突变。
Plexxikon was able to develop the drug because researchers using a gene sequencing machine had mapped the genomes of melanoma cells and found a key mutation.
目的S100A4基因在神经母细胞瘤早期转移中发挥重要作用。
Objective S100A4 gene plays an important role in neuroblastoma cell invasion and metastasis.
这一基因也能促使细胞形成畸胎瘤，但它在干细胞从开始去变成特定细胞类型的路上不仅仅只有一次作用。
The gene also allows cells to form teratomas, but it is not active once a stem cell starts down the road to becoming a specialized cell type.
分子生物学同样可以检测影响神经功能的许多疾病机理，包括多种毁坏性基因失调：肌肉萎缩症，眼癌，神经纤维瘤症，亨廷顿舞蹈病和某些类阿尔兹·海默症。
Molecular biology has also made it possible to probe the pathogenesis of many diseases that affect neural function, including several.
这些基因改变是胶质瘤恶性生物学行为的基础，但对此的了解还不是很清楚。
Such gene expression changes are the molecular basis of biological behaviors of malignant glioblastoma, but still not well known.
目的：检测并探讨分析黑色素瘤抗原基因在胃癌中的表达及其分布特点。
Objective: To investigate the expression and distribution of melanoma antigen gene in human gastric carcinoma.
目的探讨垂体瘤转化基因在垂体大腺瘤中的表达及意义。
Objective To investigate the expression of pituitary tumor transforming gene and clinical significance in pituitary marcroadenomas.
包含这两个基因的信号通路的组成性激活，可能是导致葡萄膜黑色素瘤的主要因素。
Constitutive activation of the pathway involving these two genes appears to be a major contributor to the development of uveal melanoma. (Funded by the National Institutes of Health and others. ).
许多研究表明黑色素瘤和其他皮肤癌具有家族性，但很难证明这种现象是基因的作用还是环境的作用。
Several studies have suggested melanoma and other skin cancers run in families, but it can be difficult to tease out the difference between the influence of genes and environment.
所谓高危的视网膜母细胞瘤是指有特定基因突和在初诊时就发现了肿瘤扩散。
Neuroblastoma is considered high risk if the tumors have certain genetic mutations or have already spread when the cancer is diagnosed.
美国国家神经纤维瘤化基金会：强调一组引起沿各种神经的肿瘤成长的基因疾病。
The National Neurofibromatosis Foundation of the U. S. addresses a set of genetic disorders which cause tumors to grow along various types of nerves.
提示在大多数视网膜母细胞瘤中，Rb基因的蛋白质产物缺乏。
The results suggest that Rb gene activity is possibly decreased in most cases of RB.
结果诱发携带NS基因组小鼠肺瘤结节平均数显著少于未携带NS基因组（P＜0．01）。
Results:In the group with intraperitoneal injection, the average lung tumor nodes in the group carrying NS gene were significantly lower than those of NS gene free mice( P< 0.01).
研究表明，颅内动脉瘤的易感基因在其发病机制中起着非常重要的作用。
Studies have shown that the susceptibility genes of intracranial aneurysm play a very important role in its pathogenesis.
BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。
Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.
结论黑色素瘤的发生可能与基因组不稳定性有关。
Conclusion The occurrence of melanoma might be associated with genetic genomic instability.
目的用基因芯片表达谱筛选出恶性黑色素瘤的差异基因。
ObjectiveTo identify differential genes of malignant melanoma using gene chip expression profiles.
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