寻找艾滋病高发国家的痰涂片阳性肺结核检出率的估算新方法。
To develop new methods for estimating the sputum smear-positive tuberculosis case detection rate (CDR) in a country where infection with HIV is prevalent.
年龄超过15岁的最新诊断为痰涂片阳性的肺结核病病人被随机指定给干预组和对照组。
Patients older than 15 years with newly diagnosed sputum smear-positive pulmonary TB were randomly assigned to the intervention or control group.
单独来看,所有痰涂片阳性肺结核检出率估计为72%(95%的置信区间:53- 91)。三个估值的总平均数为70%(95%的置信区间:58 - 82)。
The separate estimate for all smear-positive tuberculosis cases was 72% (95% CI: 53-91), giving an overall average for the three estimates of 70% (95% CI: 58-82).
借助这一疗法,项目下DOTS疗法覆盖率达到了100%,病例发现率达77%,结核病痰涂片呈阳性患者的治愈率达92%。
Through this approach, the project achieved 100% DOTS coverage, 77% case detection and a 92% cure rate for detected TB smear-positive patients.
痰检查、痰涂片培养或同时进行这两项检查确认了269个结核病例,其中174个病例的涂片呈阳性。
Sputum test, bacterial culture or both confirmed 269 tuberculosis cases, 174 of which were smear-positive.
18名肺结核菌痰培养呈阳性的个人没有表现出肺结核的症状,其中8人(4人在HIV状况组)的痰涂片呈阳性。
TB was asymptomatic in 18 culture-positive individuals, 8 of whom (4 in each HIV status group) had positive sputum smears.
如果假设不满15岁的人群中无人罹患结核病,那么痰涂片呈阳性的结核病的患病率为每10万人中有145人(95%的置信区间:110-180)。
The prevalence rate of smear-positive tuberculosis was 145 per 100 000 (95% confidence interval: 110–180) assuming no tuberculosis in persons aged< 15 years.
痰涂片和支气管肺泡灌洗液涂片阳性者分别为3例和10例。
The positive detection of smear was 3 cases in sputum sample, and 10 cases in BALF.
结果荧光定量pcr法检出结核杆菌阳性率显著高于痰涂片抗酸染色和培养法,其他非肺结核结果阳性率仅为2。
Results The positive rate of MTB detected with FQ-PCR was higher than that with smear acid-fast and culture of organism. The positive rate of non-tuberculosis was only 2.7%.
结果荧光定量pcr法检出结核杆菌阳性率显著高于痰涂片抗酸染色和培养法,其他非肺结核结果阳性率仅为2。
Results The positive rate of MTB detected with FQ-PCR was higher than that with smear acid-fast and culture of organism. The positive rate of non-tuberculosis was only 2.7%.
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