病理性瘢痕在临床上可分为增生性瘢痕和瘢痕疙瘩两种类型。
Pathological scars may be divided into two kinds: hypertrophic scars and keloids.
方法：对58例病理性瘢痕手术切除标本采用免疫组化方法。
Methods The tissue of abnormal scar was obtained from 58 patients who were underwent surgery .
病理性瘢痕的增生指数受P物质含量的影响较非增生性瘢痕大。
Proliferative index of pathological scar is more effected by its substance P's content than that of non-hypertrophic scar.
目的探讨结缔组织生长因子的表达与病理性瘢痕形成的相关性。
Objective to explore the correlation between the expression of connective tissue growth factor and the formation of hypertrophic scar and keloid tissues.
目的：探讨s100蛋白基因的表达情况与病理性瘢痕形成的相关性。
AIM: To investigate the correlation between expression of S100 protein gene and formation of pathological scar.
目的探讨结缔组织生长因子（CTGF）在病理性瘢痕形成中的作用。
Objective To explore the effect of connective tissue growth factor (CTGF) in the pathogenesis of pathological scar.
目的定量分析比较三维及二维培养的病理性瘢痕成纤维细胞内合成的前胶原蛋白。
Objective To compare the procollagen synthesis of pathological scar derived fibroblasts from three and two dimensional culture system .
结论：IGF - 1r的高表达和PTEN的表达下调在病理性瘢痕形成中起重要作用。
Conclusion: The over-expression of IGF-1R and down-regulation of PTEN expression may play a role in pathologic scar.
结论生物流体敷料膜能抑制创面细菌的生长，促进创面愈合，而且减少病理性瘢痕的发生率。
Conclusion the Chitosan Fluid Dressing could inhibit the growth of bacteria, accelerate the healing and bring down the pathological cicatrices.
增生性瘢痕由于目前其发病机制还不清楚，给矫形美容外科治疗病理性瘢痕带来了一定的困难。
The orthopedic and cosmetic treatment for hyperplastic scar is difficult because its pathogenesis has not been understood.
结论SP通过调控成纤维细胞凋亡相关基因的表达参与病理性瘢痕形成，该作用由SP受体介导。
Conclusion SP may play an important role in the formation of pathological scars by modulating the expression of apoptosis-associated genes, which is mediated by SP receptor.
结论构建成功的含有TRADD基因片段的重组腺病毒，可用于转染人成纤维细胞，用于检测TRADD对病理性瘢痕成纤维细胞的影响。
Conclusion the recombinant adenovirus vector carrying human TRADD gene was successfully constructed. It can be used for detecting the effects of TRADD on fibroblasts of hypertrophic scar and keloid.
结果p-ERK和PCNA蛋白在病理性瘢痕中与非病理瘢痕、正常皮肤差异有显著性（P<0.05）。相关性分析有显著性（P<0.05）。
Results The expression of PCNA and pERK were significant difference between pathologic scars group and the two control groups (P<0.05), correlativity analysis showed significant difference (P<0.05).
目的：研究基质金属蛋白酶-1（MMP-1）、金属蛋白酶组织抑制剂-1（TIMP-1）、增殖细胞核抗原（PCNA）在病理性瘢痕中的表达及意义。
Objective To study the significance of expression of Matrix Metalloproteinase-1(MMP-1) , Tissue Inhibitor of Metalloproteinase-1(TIMP-1) and Proliferating cell nuclear antigen (PCNA) in abnormal scar.
方法：采用免疫组织化学方法检测40例病理性瘢痕组织、20非病理性瘢痕组织和20例正常皮肤组织中igf - 1r、PTEN、PCNA的表达情况。
Methods: The expression of IGF-1R, PTEN, and PCNA in 40 pathologic scars, 20 non-pathologic scars, and 20 samples of normal skin tissue were detected using immunohistochemical methods.
目的：探讨病理性皮肤瘢痕癌变的相关因素。
Objective:To study the related factors on the canceration of pathological skin scar.
目的：探讨病理性皮肤瘢痕癌变的相关因素。
Objective:To study the related factors on the canceration of pathological skin scar.
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