据报道，编码p1和病毒蛋白酶3c的非复制型DNA疫苗可以诱导产生抗病毒免疫应答。
They comprise the viral capsid named P1. The non-replicating DNA vaccine, encoding P1 and the processing (3c) proteinase, was reported to produce detectable antiviral immune response.
通过构建更精确的整合酶模型，这技术使未来未来搜寻新的药物分子成为可能，这些新药物分子将能通过稳定病毒蛋白酶的结构来抑制突变病毒的抗药性。
By producing a more accurate model of integrase, the research allows further searches for new drug molecules that will inhibit the mutant drug resistant forms of this enzyme, as well.
然而，通过病毒自身蛋白酶的转变，进化在发挥着作用，并产生抗药性的菌株，这是极为常见的。
However, as often happens, evolution has got to work and generated drug-resistant strains of the virus by modifying its protease.
蛋白酶是一种蛋白质，对于引发AIDS的HIV病毒的生命周期至关重要。
Protease is a protein crucial to the life cycle of HIV, the AIDS-causing virus.
在美国旧金山，发现了一种对现有市场上的所有蛋白酶抑制剂都耐药的HIV病毒株。
An HIV strain resistant to all protease inhibitor drugs currently on the market turns up in San Francisco.
但是研究者们在本周《科学》周刊中发表的报告中说，这种新型病毒有一个弱点，那就是蛋白酶。
But this new virus has a weak point called a protease, the researchers report in this week's issue of the journal Science.
利用这些药物的互相搭配，可抵抗病毒与生俱来的变异性，但是这种策略并无法完全避免抗药性的产生，包括对蛋白酶抑制剂的抗药性。
Combinations of these agents are administered to counteract the virus's inherent mutability , but that strategy does not always ward off resistance to the medicines, including the protease inhibitors.
已有一些对抗特种病毒的药物，如用来控制HIV感染的蛋白酶抑制剂，但数量相对较少，而且易于产生病毒耐药性。
There are a handful of drugs that combat specific viruses, such as the protease inhibitors used to control HIV infection, but these are relatively few in number and susceptible to viral resistance.
我们发现了一种物质，有可能抑制蛋白酶，从而阻止病毒在试管中繁殖，那时我们真是兴奋得难以自已。
So overwhelming was the excitement that overtook us when substances were found to potently inhibit the protease enzyme, thereby blocking viral replication in the test tube.
利用毕赤酵母系统表达具有催化活性的丙型肝炎病毒（HCV）NS3蛋白酶。
Non-structural protein 3(NS3) of hepatitis C virus (HCV), the serine protease, is a key functional protein, which is responsible for the processing of HCV polyprotein.
结果：分析支气管肺泡灌洗液(BALF)中炎症细胞、炎症介质、蛋白酶、组织病理学、病毒滴定率、T细胞。
Results: inflammatory cell influx into the bronchoalveolar lavage (BALF), inflammatory mediators, proteases, histopathology, viral titres and t lymphocyte profiles were analyzed.
目的：构建及鉴定载入金属蛋白酶组织抑制因子1（TIMP鄄1）的重组腺相关病毒载体。
Objective: To construct and identify recombinant adeno-associated virus encoding rat tissue inhibitor of metalloproteinase-1(TIMP-1) full length cDNA.
本发 明还提供了提高在表达这种异源蛋白酶或蛋白酶原的细胞内生长的流感病毒的效价 的方法。
The invention also provides methods for increasing the titer of influenza viruses grown in cells that express such a heterologous protease or pro-protease.
目的人鼻病毒3c蛋白酶具有酶切物异性强且在低温下仍保持较强酶活性的特点而被用作工具酶。
Objective Application of human rhinovirus 14 3c protease as a tool-enzyme for more stringent sequence specificity and efficient cleavage at low temperature.
该疗法将蛋白酶抑制剂与多种抗病毒的药物混合使用，使艾滋病得到有效的控制。
The therapy will be a variety of protease inhibitors and antiviral drugs mixed use, so that the effective control of AIDS.
目的建立原材料胰蛋白酶中猪细小病毒的PCR检测方法。
Objective To establish PCR assay of Porcine Parvovirus detection in Trypsin.
病毒性肝炎（乙型或丙型）是大结节型肝硬化的最常见病因，Wilson’s病和alpha-1-抗胰蛋白酶缺陷也能产生肝大结硬化。
Viral hepatitis (B or C) is the most common cause for macronodular cirrhosis. Wilson's disease and alpha-1-antitrypsin deficiency also can produce a macronodular cirrhosis.
可以肯定，新的特异性抑制剂——蛋白酶抑制剂和聚合酶抑制剂对某些患者会非常有效，因为这些药物能通过一种特殊的方式非常有效地减少病毒复制。
The first slope, the first rapid decrease of viral replication is related to the inhibition of the replication by the antiviral effect of interferon.
如果你正在服用蛋白酶抑制剂，如艾滋病毒治疗，医生可能会建议25毫克的剂量，并可能会限制你最大的单剂量在48小时内，25毫克伟哥。
If you are taking protease inhibitors, such as for the treatment of HIV, your doctor may recommend a 25 mg dose and may limit you to a maximum single dose of 25 mg of VIAGRA in a 48-hour period.
对其氨基酸序列进行分析，蛋白酶裂解位点序列除LH株为GKRKKR外，其余三株为RRRKKR，为高致病性禽流感病毒的特征序列；
The proteolytic cleavage sites were all hexylbasic amino acids RRRKKR, with exception of LH (GKRKKR), which were the characteristic sequence of the highly pathogenic strains;
对其氨基酸序列进行分析，蛋白酶裂解位点序列除LH株为GKRKKR外，其余三株为RRRKKR，为高致病性禽流感病毒的特征序列；
The proteolytic cleavage sites were all hexylbasic amino acids RRRKKR, with exception of LH (GKRKKR), which were the characteristic sequence of the highly pathogenic strains;
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