病毒基因表达的改变对控制宿主细胞命运的基因网络具有显著的非线性作用,其可以决定细胞裂解或是进入潜伏状态。
Changes in viral gene expression can have a dramatic nonlinear effect on gene networks that control whether viruses burst out of the host cell or enter a latent state.
研究人员使用脐带中和盈利性实验室里的定向造血干细胞,通过在试管中进行试验演示出,病毒不但可以感染细胞而且还能保持潜伏状态。
Using HPCs from umbilical cords and commercial LABS, the researchers demonstrated in test-tube experiments that the virus not only infected the cells but also could remain latent.
通常它处于潜伏状态,但是因为压力、亚健康状态,或是抗癌药物的使用,病毒微粒再次返回皮肤而引起疼痛性皮疹。
It usually lays dormant, but because of stress or ill health or treatment with anti-cancer drugs, the viral particles migrate back out to the skin and cause a painful rash.
许多病毒作为“永久的乘客”在宿主终生都处于潜伏状态,不引起明显症状,Virgin说。
Many lurk for the lifetime of their hosts "as permanent passengers" without causing overt symptoms, Virgin said.
整合后它有时不表达但维持在一种潜伏状态(原病毒)。
After integration it is sometimes not expressed but maintained in a latent state (PROVIRUSES).
结论EBV相关胃癌和EBV阳性鼻咽癌组织中病毒潜伏期基因启动子的甲基化状态不同,甲基化是调控EBV潜伏期基因启动子活动的重要机制之一。
Conclusion The methylation status of EBV latent gene promoters in EBVaGC and NPC is different, methylation is one of important mechanisms in regularing the activity of EBV latent gene promoters.
结论EBV相关胃癌和EBV阳性鼻咽癌组织中病毒潜伏期基因启动子的甲基化状态不同,甲基化是调控EBV潜伏期基因启动子活动的重要机制之一。
Conclusion The methylation status of EBV latent gene promoters in EBVaGC and NPC is different, methylation is one of important mechanisms in regularing the activity of EBV latent gene promoters.
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