她的团队已经在早期做了大量的工作,至少在小鼠中,疱疹病毒感染的神经细胞导致了beta-淀粉的沉积,而这是淀粉样蛋白斑块的主要成分。
Earlier work done by her team has shown that, in mice at least, the herpes infection of nerve cells induces accumulation of beta amyloid, the main component of amyloid plaques.
容纳性细胞允许转录活化蛋白的转录和翻译,其激活病毒的早期基因和溶解性周期。
Permissive cells allow the transcription and translation of the transcriptional activator protein(ZEBRA), which activates the early genes of the virus and the lytic cycle.
在腺病毒载体的构建过程中,早期和晚期启动子的选择、构建以及去除末端蛋白(TP)、克隆末端序列是至关重要的。
The selection and cloning of early and late promoters and removal of adenovirus terminal protein (TP) are very important in construction of adenovirus vector.
表明,UL34基因对病毒的早期包装、成熟和出芽以及对UL31蛋白和核纤层蛋白在感染细胞中的正确定位都具有重要作用。
Then, the important roles of the gene in viral primary envelopment, mature and budding, proper location of the UL31 protein and lamin protein in cells infected with the virus were pointed out.
表明,UL34基因对病毒的早期包装、成熟和出芽以及对UL31蛋白和核纤层蛋白在感染细胞中的正确定位都具有重要作用。
Then, the important roles of the gene in viral primary envelopment, mature and budding, proper location of the UL31 protein and lamin protein in cells infected with the virus were pointed out.
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