人类疾病动物模型的设计原则和复制方法。
Designing principles and reproducing methods for animal model of human diseases.
目的建立H5N1禽流感病毒感染ICR小鼠的疾病动物模型。
Objective To create a ICR mouse model infected with avian influenza A(H5N1)virus.
本文就基因打靶技术及其在人类疾病动物模型研究中的应用做一介绍。
Gene targeting technology and its application in research of animal model of human disease were briefed in this paper.
结论：表明通过辨析自发性疾病动物模型的中医证候特征，可以建立稳定、均一的病证结合动物模型。
Conclusion: Via differentiate and analyse the characteristic of Chinese medical syndrome of spontaneously disease animal model, Can establish stabilization and homogeneous animal models which...
人类疾病动物模型在医学研究中起着非常重要的作用，而自然发生的人类疾病已远远不能满足医学研究的需要。
Animal model of human disease plays an important role in medical research, but spontaneous human disease cannot satisfy needs of medical research.
简要介绍了应用裸小鼠以来建立的各种皮肤疾病动物模型及裸小鼠在皮肤毒理学上的应用，并展望了裸小鼠在皮肤病学和皮肤毒理学应用中的前景。
In this paper, animal model of dermatosis based on nude mice and the use of nude mice in dermatotoxicology are described and the prospective development is also discussed.
这些疾病的动物模型，有助于理解如何受影响的基因和蛋白质功能障碍疾病的病理。
Animal models of these diseases are proving useful to understand how dysfunction of affected genes and proteins contributes to disease pathology.
结论小型猪的混合唾液流率与人接近，是唾液疾病研究中较为理想的大型实验动物模型。
It is considered that minipig is a good large laboratory animal model for investigation of oral saliva gland diseases.
动物模型模拟这种状况对于我们能熟悉疾病的进展以及对早期椎间盘退变的治疗都是很重要的。
Animal models simulating this condition are essential for understanding disease progression and for development of therapies aimed at early intervention.
“你可以复制你想要的任何一种人类疾病的动物模型。”史密斯在昨天接受电话采访时说道。
"If you want to make a model of a specific human disease, you can," Smithies said yesterday in a telephone interview.
动物模型建立对于病理机制认识和疾病防治有重要价值。
The establishment of the animal model would contribute to the investigation of pathogenesis.
在动物模型中，摄取足够的营养并且限制热量的摄入能够减少慢性疾病发生的危险，并能延长寿命。
In rodent models, calorie restriction with adequate nutrient intake decreases the risk of developing chronic disease and extends maximum life span.
目前，这样的动物模型在实验研究中已经得以广泛应用，可助于研究人员更好地理解疾病的起因和寻找治疗的方法和药物。
Such mice, now commonly used in laboratory experiments, could help researchers better understand the origins of disease and find treatments and medicines.
摘要猪不仅可以为人类提供重要的肉产品，而且作为良好的动物模型在人类疾病研究中发挥着重要的作用。
Abstract: Besides supplying the significant meat product for human being, pigs also play a vital role in the research fields of human disease as the fabulous animal models.
目的：为围绝经期疾病的动物模型的选择和制备提供参考。
Objective:To offer the references for selecting and preparing animal models of perimenopause.
由于缺乏有效的体外细胞培养体系和动物模型，人博卡病毒与人类呼吸道或胃肠道疾病的临床关联尚且未知。
Since no in vitro cell culture systems and animal models are available, whatever role HBoVs plays in respiratory infections and gastrointestinal illness remains uncertain.
目的对急性脑静脉闭塞动物模型加以改进，拟建立一个稳定的类似临床疾病的动物模型。
Objective to improve the model of acute cerebral venous occlusion and establish a stable animal model to be similar to clinical disease.
牛血清白蛋白是一种球蛋白，目前已成功运用于血管性疾病实验动物模型的诱导及体外实验中。
Bovine serum albumin is one globulin, which has been successfully applied on animal models and vitro study on vascular disease.
其中大多数的结论直接来自于对大鼠膜性肾病（或称海曼肾炎）模型的研究，该动物模型很相似地模拟了人类该类疾病的临床和病理特征。
Most of these have come directly from studies carried out in the Heymann nephritis models of MN in rats, which closely simulate the clinical and pathologic features of the human disease.
同时他还说：“这个研究结果强调了这样一个事实——血脑屏障的通透性改变是发生象实验性变应性脑脊髓炎(一种多发性硬化病的动物模型)这类中枢神经系统感染性疾病的重要因素。”
"This puts an emphasis on the fact that blood brain permeability changes are an important aspect of the development of a CNS inflammatory disease like EAE, an animal model of MS," he says.
结论椎间盘退变的动物模型是研究椎间盘退变性疾病发病机制的一种重要手段，同时为退变椎间盘的修复研究提供良好的实验载体。
Conclusion Animal model of intervertebral disc degeneration is an important path for revealing the pathogenesis of human disc degeneration, and play an important role in testing novel interventions.
研究者在每个大鼠品系建立实验性自身免疫性脑脊髓炎动物模型，并检测疾病进展过程中这些动物都有哪些变化。
The researchers established EAE in each mouse strain and examined what was common to all of the animals when they developed disease.
目的制作与人肾盂肾炎相似的动物模型，为临床治疗急慢性泌尿系感染性疾病打下实验基础。
Objective to made the animal model which is similar to the human pyelonephritis to strengthen the experimental basis for the therapy of acute urologic infectious disease.
结论体外定点突变系统可以对基因进行精细的修饰，为建立更精确地模拟人类疾病的动物模型打下基础。
Conclusion the site specific point mutation system can modify human gene in vitro more accurately. It is useful in the setting up of animal models.
结论体外定点突变系统可以对基因进行精细的修饰，为建立更精确地模拟人类疾病的动物模型打下基础。
Conclusion the site specific point mutation system can modify human gene in vitro more accurately. It is useful in the setting up of animal models.
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