提 高了纳米粒子的载药量及包封率,控制了疏水性药物的突释现象。
The invention improves the carrier and packing rate of nanometer particles, and controls the instant release condition of hydrophobic drug.
利用非微粒脂质给药系统,药物不必经过溶出的步骤,从而可以显著的提高疏水性药物的口服吸收。
Oral absorption of hydrophobic drugs can be significantly improved using lipid-based non-particulate drug delivery systems, which avoid the dissolution step.
本发明制备工艺简单,所 得纳米粒子粒径均匀,粒度分布较窄,对疏水性药物有较高的载药量和包封率。
The invention has simple process, uniform grain diameter, narrow graininess distribution, high carrier and packing rate on hydrophobic drug.
肿瘤是目前危害人类健康的重大疾病之一,而临床应用的抗肿瘤药大多数为疏水性药物,需要载体增溶后才能使用。
Tumor is one of the important diseases threatening the health of human beings. Most of antitumor drugs used in clinical are hydrophobic ones and need to be solubilized by carriers.
肿瘤是目前危害人类健康的重大疾病之一,而临床应用的抗肿瘤药大多数为疏水性药物,需要载体增溶后才能使用。
Tumor is one of the important diseases threatening the health of human beings. Most of antitumor drugs used in clinical are hydrophobic ones and need to be solubilized by carriers.
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