我们进一步用膜通道阻断剂验证,发现胞外钙的流入主要是通过N型钙通道和电压门控钠通道流入胞内的。
Furthermore, the external calcium was found to influx mainly through N-type calcium channels and voltage-gated sodium channels.
结论野木瓜注射液除影响髓鞘和轴突膜结构外还通过调制初级感觉神经元电压门控性钠通道,影响痛觉信息中枢传入产生镇痛作用。
Conclusion The analgesic effect of IS was presumably caused by modulation of voltage-gated sodium channels in primary sensory neurons besides structure destruction of myelin sheath and axon membrane.
目的:研究血竭对大鼠背根神经节细胞电压门控性钠通道电流的影响。
Objective: to investigate the effects of blood resin on voltage gated sodium channel current in freshly isolated rat DRG neurons.
结果:血竭剂量依赖地抑制单个DRG细胞电压门控性钠通道电流,高剂量的血竭抑制作用不可逆。
The inhibition effect was irreversible at high dosage. Conclusion: blood resin inhibits the voltage gated sodium channel currents, which may well provide some analgesic effects.
结果:血竭剂量依赖地抑制单个DRG细胞电压门控性钠通道电流,高剂量的血竭抑制作用不可逆。
The inhibition effect was irreversible at high dosage. Conclusion: blood resin inhibits the voltage gated sodium channel currents, which may well provide some analgesic effects.
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