在某些噬菌体中,5-羟甲基胞嘧啶取代了胞嘧啶。40年代后期,查加夫。
In certain bacteriophages, 5 - methylol cytosines have substituted for the cytosine. In the late 40s, looks up Garv e.
新发现的位置核苷酸,叫做强甲基胞嘧啶,位于动物细胞内,提示着有新的基因表达调控机制。
The discovery of a previously unknown nucleotide, called hydroxymethylcytosine, inside animal cells suggests a new mechanism for regulating gene expression.
非甲基化胞嘧啶残基的亚硫酸氢盐转换,接着是检测方法,例如不同位点的测序已经被接受为检测5甲基胞嘧啶的金标准。
Bisulphite conversion of unmethylated cytosine residues followed by detection methods such as sequencing of distinct loci has become accepted as the gold standard for detecting 5-methylcytosines.
工作小组关注甲基化作用,是指一个甲基群被放在DNA序列的胞嘧啶上面。
The team looked at methylation, in which a methyl group is placed onto cytosine in DNA sequences.
胞嘧啶甲基化是否能够解释这种差异还有待考察,但是的确是有些什么东西存在着。
Whether cytosine methylation is the explanation for this difference has yet to be tested, but something is clearly happening.
外因遗传是一种可以传给下一代细胞的基因调控过程,最常见的方式是通过甲基化作用来完成,该作用可以让甲基(由一个碳原子和三个氢原子组成)附着于腺嘌呤或胞嘧啶上。
Epigenetics is a type of gene regulation that can be passed from a cell to its daughters. The most common mechanism is methylation.
这些甲基团只粘附于特定胞嘧啶碱基-DNA四个组成成分之一。
The methyl groups are attached only to specific cytosine bases - one of the four building blocks of DNA.
在DNA甲基化的胞嘧啶碱基在许多真核生物的表观遗传调控提供了一层正常的生物学和疾病有着重要的意义。
Methylation of cytosine bases in DNA provides a layer of epigenetic control in many eukaryotes that has important implications for normal biology and disease.
应用甲基化敏感扩增多态性(MSAP)技术对24个脐橙品种胞嘧啶甲基化模式和程度进行评估。
The extent and pattern of cytosine methylation in 24 navel orange cultivars, genomes were assessed by using the technique of methylation-sensitive amplified polymorphism (MSAP).
它依赖于用亚硫酸氢钠处理后,非甲基化的 胞嘧啶选择性的去氨基为 尿嘧啶,通常接着所选的靶向区域的PCR扩增。
It relies upon the selective deamination of unmethylated cytosine to uracil after treatment with sodium bisulphite, usually followed by PCR amplification of the chosen target region.
胞嘧啶的甲基化能够沉默植物、脊椎动物和真菌的转座元件,同时也能调控基因的表达。
Cytosine methylation silences transposable elements in plants, vertebrates, and fungi but also regulates gene expression.
本文首次运用MSAP技术对脐橙品种进行胞嘧啶甲基化分析表明,使用MSAP检测脐橙品种多态性非常有效。
This paper is the first time to analyse cytosine methylation in navel oranges using MSAP, indicating MSAP technique is efficient for detection of cytosine methylation in navel orange genomes.
哺乳动物似乎具有利用胞嘧啶甲基化提供一个可继承的机制,用来改变DNA -蛋白质相互作用,辅助这个沉默。
Mammals appear to have taken advantage of the possibilities afforded by cytosine methylation to provide a heritable mechanism for altering DNA-protein interactions to assist in such silencing.
此前,科学家们已对第5种碱基有所了解——当一个化学标签或甲基被固定到一个胞嘧啶上时,第5种碱基就会出现。
Much is known about the "fifth base, " 5-methylcytosine, which arises when a chemical tag or methyl group is tacked onto a cytosine.
近年来发现4 -氧代二氢喹啉类和含有非甲基化胞嘧啶鸟嘌呤二核苷酸序列的寡脱氧核苷酸为抗单纯疱疹病毒的新药。
This review describes two kinds of new anti-HSV drugs, 4-oxo-dihydroquinolines and cytosine-phosphate-guanine (CpG) -containing oligodeoxynucleotide (ODN), which have been developed in recent years.
应用5-杂氮脱氧胞嘧啶处理上述白血病细胞系,观察去甲基化处理对失活基因的影响;
Then it was observed whether the inactived genes in leukemia cell lines were actived after the treatment with 5-aza-deoxycytosin, a kind ofdemethylation agent .
应用5-杂氮脱氧胞嘧啶处理上述白血病细胞系,观察去甲基化处理对失活基因的影响;
Then it was observed whether the inactived genes in leukemia cell lines were actived after the treatment with 5-aza-deoxycytosin, a kind ofdemethylation agent .
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