本发明涉及从阿德福韦制备阿德福韦酯二氧新戊酸双氧甲基酯的方法。
The invention relates to a method for preparing adefovir dipivoxil dual oxygen methyl pivalate from adefovir.
结果表明2-甲基丁酸是艰难梭菌的特征性产物，以前曾被其他作者错误地鉴定为异戊酸。
Results showed 2-methyl butyric acid was the characteristic product of C. difficile and was wrong identified as isovaleric acid by others.
目的：建立一种快速、简单的测定大鼠血浆中阿德福韦酯水解产物阿德福韦单特戊酸甲基酯和阿德福韦的离子对反相高效液相色谱方法。
Objective:To establish a rapid and simple HPLC method for the determination of adefovir dipivoxil and its metabolites in the rat plasma in vitro.
目的：建立一种快速、简单的测定大鼠血浆中阿德福韦酯水解产物阿德福韦单特戊酸甲基酯和阿德福韦的离子对反相高效液相色谱方法。
Objective:To establish a rapid and simple HPLC method for the determination of adefovir dipivoxil and its metabolites in the rat plasma in vitro.
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