目的构建并评价垂体生长激素腺瘤靶向性基因治疗系统。
Objective To construct and study the targeted gene therapy system for growth hormone- secreting pituitary tumors.
肿瘤出血多见于生长激素腺瘤(22.2%)及泌乳素腺瘤(21.4%)。
Hemorrhage of adenomas was mostly found in GH adenomas (22.2%) and PRL adenomas (21.4%).
方法将17例垂体生长激素腺瘤组织以不同的方法固定处理后，分别使用电子显微镜和光学显微镜进行观察。
Methods Growth hormone pituitary adenoma specimens from 17 patients were fixed and observed under electron microscope and light microscope.
目的利用GE7系统介导的生长激素启动子调控毒性基因治疗裸鼠垂体生长激素腺瘤，评价该系统的治疗效果。
Objective To study the effects of gene therapy system mediated by GE7 system and controlled by human growth hormone promoter on somatotroph adenomas of nude mice.
目的利用GE7系统介导的生长激素启动子调控毒性基因治疗裸鼠垂体生长激素腺瘤，评价该系统的治疗效果。
Objective To study the effects of gene therapy system mediated by GE7 system and controlled by human growth hormone promoter on somatotroph adenomas of nude mice.
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