• 例如艾比特思名为表皮生长因子受体(EGFR)的细胞表面蛋白结合

    Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR).

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  • 肺癌表皮生长因子受体基因临床生物学特点

    Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers.

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  • 目的观察纤维细胞生长因子受体2 (FGFR2)在小鼠发生发育中的表达规律定位,探讨FG - FR2小鼠肾发生发育关系

    Objective to observe the expression rules and sites of fibroblast growth factor receptor 2 during kidney development of mouse and investigate the correlation of FGFR2 with kidney development.

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  • 目的研究表皮生长因子受体增殖细胞核抗原肿瘤中的表达及其临床意义

    Objective: To study the expression of EGFR and PCNA protein in human gastric neoplasm and its clinical significance.

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  • 转录最高的基因功能相关,细胞粘附基质蛋白生长因子受体蛋白酶

    The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.

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  • 然后两分别神经蛋白神经生长因子受体蛋白免疫荧光染色、激光聚焦显微镜检测移植效果。

    Effects of both groups were assayed with neurofilament nf protein and nerve growth factor receptor protein immunofluorescent double labelled staining laser confocal microscopy.

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  • 目的研究角质形成细胞生长因子(KGF)及其受体(KGFR)反义核苷酸KGF介导细胞周期凋亡变化的抑制作用。

    Objective to investigate the effects of keratinocyte growth factor (KGF) and KGF receptor (KGFR) antisense oligonucleotide (ASODN) on cell cycle and apoptosis of HaCat cells.

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  • 目的观察第3 ~ 8中肾发育生长因子及其受体表达

    Objective: to observe the development of mesonephros and the expression of growth factors and their receptors in human embryo of 3th-8th weeks.

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  • 表皮生长因子受体(EGFR)及其配体过表达疾病迅速进展化疗耐药有密切的联系

    The overexpression of the epidermal growth factor receptor and its ligands correlates with rapidly progressive disease and resistance to chemotherapy.

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  • 单克隆抗体治疗靶点包括细胞表面抗原生长因子受体

    Those targets for monoclonal antibodies therapy include cellular growth factor receptors and cell surface antigens, etc.

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  • 例如委员会使用关于单克隆抗体西妥单抗帕尼单抗(它们抑制转移性直肠癌表皮生长因子受体egfr)的数据

    For example, the Panel used data for the monoclonal antibodies cetuximab and panitumumab, which inhibit the EGF receptor (EGFR) in metastatic colorectal cancer.

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  • 目前,市场一些针对肝细胞生长因子受体成纤维细胞生长因子受体药物

    There are some very interesting agents on the market which will target hepatocyte growth factor receptor and fibroblast growth factor receptors.

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  • 其中,我们对于发生表皮生长因子受体EGFR突变间变淋巴瘤激酶ALK重排的非小细胞肺癌患者治疗取得显著进展

    We have made significant progress in the treatment of patients with mutations in the Epidermal Growth Factor Receptor (EGFR) and rearrangements involving anaplastic lymphoma kinase (ALK).

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  • 目的观察表皮生长因子受体EGFR口腔复发性阿弗他溃疡(RAU) 组织中蛋白基因表达变化

    Objective To explore the expression change of protein and mRNA of EGFR(epidermal growth factor receptor)in RAU(recurrent aphthous ulcer).

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  • 应用毛细管电泳(ace)分析方法对表皮生长因子受体(EGFR)多肽配体GE11之间结合能力进行分析。

    The binding ability of new peptide ligand GE11 and epidermal growth factor receptor (EGFR) was analyzed by affinity capillary electrophoresis (ACE) method.

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  • 目的克隆人表皮生长因子受体HER2基因建立共表达HER2基因雌激素受体(ER)基因MCF-7细胞模型。

    Objective To clone human epidermal growth factor receptor (HER2) gene and establish a MCF-7 cell line with stable co-expression of HER2 and estrogen receptor (ER).

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  • 目的研究胰岛素生长因子- I (IGF - I)、胰岛素样生长因子- II (IGF - II)胰岛素样生长因子i型受体(IGF - IR)胃癌中的表达及其临床病理关系

    Objective: the aims of this study were to investigate the expression of IGF-I, IGF-II and IGF-IR in gastric cancer and their relationship with clinicopathological factors.

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  • 贝伐单抗阻断血管内皮生长因子(VEGF)受体活性肿瘤血管生成,增殖转移重要因子

    Bevacizumab blocks the action of the vascular endothelial growth factor (VEGF) receptor, a key factor in tumor angiogenesis, growth, and metastasis.

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  • 目前认为垂体腺瘤发生基因突变生长因子细胞受体转录因子细胞信号通路等有关

    The pathogenesis of pituitary adenomas is considered to be related with gene mutation, growth factors, cell receptors, transcription factors, and cellular signaling pathways.

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  • 采用分子动力学MM/PBSA相结合的方法预测表皮生长因子受体4-苯胺喹 啉类抑制剂的相互作用模式

    The possible binding mode between EGFR and a 4-anilinoqunazoline inhibitor was predicted by using molecular dynamics and MM/PBSA.

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  • 主要观察指标:息肉组织正常黏膜组织血管内皮生长因子及其受体表达

    MAIN OUTCOME MEASURES: The expression of VEGF and its receptors in polypous tissue and in normal nasal mucosa tissues.

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  • 表皮生长因子受体结构通过同源蛋白模方法得到抑制剂靶酶结合复合物结构则通过分子力学分子动力学结合的方法计算得到。

    The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.

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  • 表皮生长因子受体结构通过同源蛋白模方法得到抑制剂靶酶结合复合物结构则通过分子力学分子动力学结合的方法计算得到。

    The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.

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