例如,艾比特思和名为表皮生长因子受体(EGFR)的细胞表面蛋白的结合。
Erbitux, for example, binds to a cell-surface protein called epidermal growth-factor receptor (EGFR).
肺癌中表皮生长因子受体基因的临床和生物学特点。
Clinical and Biological Features Associated With Epidermal Growth Factor Receptor Gene Mutations in Lung Cancers.
目的观察成纤维细胞生长因子受体2 (FGFR2)在小鼠肾发生发育中的表达规律和定位,探讨FG - FR2与小鼠肾发生发育的关系。
Objective to observe the expression rules and sites of fibroblast growth factor receptor 2 during kidney development of mouse and investigate the correlation of FGFR2 with kidney development.
目的:研究表皮生长因子受体和增殖细胞核抗原在胃肿瘤中的表达及其临床意义。
Objective: To study the expression of EGFR and PCNA protein in human gastric neoplasm and its clinical significance.
转录最高的基因与功能相关,如细胞粘附,基质蛋白,生长因子,受体和蛋白酶。
The most highly transcribed genes relate to functional groupings such as cell adhesion, matrix proteins, growth factors and receptors, and proteases.
然后两组分别以神经丝蛋白和神经生长因子受体蛋白免疫荧光双标染色、激光共聚焦显微镜检测移植效果。
Effects of both groups were assayed with neurofilament nf protein and nerve growth factor receptor protein immunofluorescent double labelled staining laser confocal microscopy.
目的研究角质形成细胞生长因子(KGF)及其受体(KGFR)反义寡核苷酸对KGF介导的细胞周期和凋亡变化的抑制作用。
Objective to investigate the effects of keratinocyte growth factor (KGF) and KGF receptor (KGFR) antisense oligonucleotide (ASODN) on cell cycle and apoptosis of HaCat cells.
目的:观察第3 ~ 8周人胚中肾的发育和生长因子及其受体的表达。
Objective: to observe the development of mesonephros and the expression of growth factors and their receptors in human embryo of 3th-8th weeks.
表皮生长因子受体(EGFR)及其配体的过表达与疾病的迅速进展和对化疗的耐药有密切的联系。
The overexpression of the epidermal growth factor receptor and its ligands correlates with rapidly progressive disease and resistance to chemotherapy.
单克隆抗体治疗的靶点包括细胞表面抗原和生长因子受体等。
Those targets for monoclonal antibodies therapy include cellular growth factor receptors and cell surface antigens, etc.
例如,委员会使用的关于单克隆抗体西妥昔单抗和帕尼单抗(它们抑制转移性结直肠癌的表皮生长因子受体egfr)的数据。
For example, the Panel used data for the monoclonal antibodies cetuximab and panitumumab, which inhibit the EGF receptor (EGFR) in metastatic colorectal cancer.
目前,市场上有一些针对肝细胞生长因子受体和成纤维细胞生长因子受体的药物。
There are some very interesting agents on the market which will target hepatocyte growth factor receptor and fibroblast growth factor receptors.
其中,我们对于发生表皮生长因子受体(EGFR)突变和间变淋巴瘤激酶(ALK)重排的非小细胞肺癌患者的治疗取得了显著的进展。
We have made significant progress in the treatment of patients with mutations in the Epidermal Growth Factor Receptor (EGFR) and rearrangements involving anaplastic lymphoma kinase (ALK).
目的观察表皮生长因子受体(EGFR)在口腔复发性阿弗他溃疡(RAU) 组织中蛋白和基因表达变化。
Objective To explore the expression change of protein and mRNA of EGFR(epidermal growth factor receptor)in RAU(recurrent aphthous ulcer).
应用亲和毛细管电泳(ace)分析方法,对表皮生长因子受体(EGFR)和新多肽配体GE11之间的结合能力进行分析。
The binding ability of new peptide ligand GE11 and epidermal growth factor receptor (EGFR) was analyzed by affinity capillary electrophoresis (ACE) method.
目的克隆人表皮生长因子受体(HER2)基因,建立共表达HER2基因和雌激素受体(ER)基因的MCF-7细胞模型。
Objective To clone human epidermal growth factor receptor (HER2) gene and establish a MCF-7 cell line with stable co-expression of HER2 and estrogen receptor (ER).
目的:研究胰岛素样生长因子- I (IGF - I)、胰岛素样生长因子- II (IGF - II)和胰岛素样生长因子i型受体(IGF - IR)在胃癌中的表达及其与临床病理的关系。
Objective: the aims of this study were to investigate the expression of IGF-I, IGF-II and IGF-IR in gastric cancer and their relationship with clinicopathological factors.
贝伐单抗阻断血管内皮生长因子(VEGF)受体活性,是肿瘤血管生成,增殖和转移的重要因子。
Bevacizumab blocks the action of the vascular endothelial growth factor (VEGF) receptor, a key factor in tumor angiogenesis, growth, and metastasis.
目前认为垂体腺瘤的发生与基因突变、生长因子、细胞受体、转录因子和细胞信号通路等有关。
The pathogenesis of pituitary adenomas is considered to be related with gene mutation, growth factors, cell receptors, transcription factors, and cellular signaling pathways.
采用分子动力学和MM/PBSA相结合的方法预测了表皮生长因子受体和4-苯胺喹 啉类抑制剂的相互作用模式。
The possible binding mode between EGFR and a 4-anilinoqunazoline inhibitor was predicted by using molecular dynamics and MM/PBSA.
主要观察指标:鼻息肉组织和正常鼻黏膜组织血管内皮生长因子及其受体的表达。
MAIN OUTCOME MEASURES: The expression of VEGF and its receptors in polypous tissue and in normal nasal mucosa tissues.
表皮生长因子受体的三维结构通过同源蛋白模建的方法得到,而抑制剂和靶酶结合复合物结构则通过分子力学和分子动力学结合的方法计算得到。
The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.
表皮生长因子受体的三维结构通过同源蛋白模建的方法得到,而抑制剂和靶酶结合复合物结构则通过分子力学和分子动力学结合的方法计算得到。
The 3d structure of EGFR was constructed using homology modeling, and the complex structures between receptor and ligands were predicted by using molecular mechanics and molecular dynamics.
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