结论超生理剂量地塞米松可用于建立骨骼肌细胞的损伤模型。
Conclusion Dexamethasone beyond physical dosage could be applied to establish injury model of skeletal muscle cells.
目的探讨生理剂量的睾酮能否改善老年雄性糖尿病大鼠的糖代谢。
ObjectiveTo study the effects of testosterone of physiological dose on glucose and lipids metabolism of male aging rats with diabetes.
目的:观察长期使用外源性超生理剂量皮质类固醇对大白鼠小肠吻合口愈合的影响及维生素a的干预效应。
Objective: to observe the influence of over-physiological dose of corticosteroids on the healing of small intestinal anastomosis in rats with interfered effect of vitamin a.
结果超生理剂量地塞米松可抑制骨骼肌细胞的增殖,降低其SOD水平,提高MDA水平,并造成细胞的损伤与钙超载。
Results Dexamethasone beyond physical dosage could suppress cells proliferation, reduce SOD level, increase MDA, and cause cells injury and Ca 2+ overloading.
值得注意的是,在人细胞的研究实验中,需要给予T3的超生理剂量(10nmol/L)才能获得这种效应,而生理剂量不能诱导出反应。
Notably, in the study in human cells, a supraphysiological dose of T3 (10 nmol/l) was required to obtain the effect, while physiological doses did not induce a response.
行为改变、生理学上的变化或代谢解毒等抗性机制能够降低毒物到达靶标的有效剂量。
Mechanisms of resistance, such as behavioral change, physiological modification or metabolic detoxification, decrease the effective dose available at the target site.
戒断症状指停止使用药物或减少使用剂量或使用拮抗剂占据受体后所出现的特殊的心理生理症群。
Withdrawal state: it is the physiological and psychological symptoms occurring after stopping using or reducing the dose of certain drug or using antagonist to occupy the receptor.
目的:探讨治疗剂量超声波对青年血浆内皮素(et)、心钠素(ANF)和心脏电生理学的影响。
Objective: to explore the influence of the therapeutic dose ultrasound on plasma endothelin (et), atrial natriuretic factor (ANF) and heart electrophysiology in normal subjects.
正常对照组同法皮下注射相应剂量生理盐水。
The rats of normal control group were also subcutaneously injected the saline solution with the same dosage.
再灌注组给予生理盐水,给药剂量、时间和方法同依达拉奉组。
Rats in reperfusion group received physiologic saline with the same dose, method, time as the edaravone group.
结果辛伐他汀主要副作用有肌毒性、肝损害和肾功能损害等,且与剂量、联合用药及生理状况等有关。
Results: Adverse effects were mostly seen on the muscle, liver and kidney, etc. They were relative with dosage, drug combination, health condition and others.
目的:探讨小剂量激素替代(HRT)治疗对绝经早期妇女生理、心理健康的影响。
Objective: To explore the effect of low-dose hormone replacement therapy (HRT) on physiological and psychological health in women at early stage of menopause.
对照组小鼠皮下注射同体积的生理盐水及同剂量的纳洛酮。
Mice in control group were injected with the same volume of saline and the same dosage of naloxone.
模型组与正常对照组每日灌服等剂量的生理盐水。
The normal and model groups were administrated with same quantity of physiology brine.
前言: 目的:观察超剂量儿茶酚胺对去甲肾上腺素性心肌病动物模型病理生理指标的影响。
Objective:To observe the influence of over dosage catecholamine on animal models of congestive cardiomyopathy made by noradrenalin in pathology and physiology.
观察组患者在此基础上加用小剂量肝素,对照组加用等剂量生理盐水。
Observation group patients were treated with low dose of heparin on the basis of the above treatment.
对照组术中、术后均给予相同剂量的生理盐水作为对照。
The control group received the same dosage of normal saline at operation and after operation.
结论常用的药效学S型剂量效应曲线拟合的数学模型中,Hill系数无生理学含义。
CONCLUSION the Hill coefficient is considered not any physiological meanings in the mathematics model usually used in fitting pharmacodynamics s dose-effect curve.
结果:应用魟鱼软骨多糖各剂量组,小鼠原发瘤抑制率、肺转移数与生理盐水组比较差异有显著性(P<0.05,P<0.01);
Results:There were significant differences from inhibitory rates of primary tumor and the number of lung metastasis focuses between RCG groups and Saline group(P<0.05, P<0.01);
通过小鼠尾鳞片实验模型,设生理盐水组、低、高剂量组,观察各组对小鼠尾部鳞片颗粒层形成的影响。
The animal model of tail scales of mouse was taken. To be divided into three groups: the normal saline negative control group, the low dose group, the high dose group.
通过小鼠尾鳞片实验模型,设生理盐水组、低、高剂量组,观察各组对小鼠尾部鳞片颗粒层形成的影响。
The animal model of tail scales of mouse was taken. To be divided into three groups: the normal saline negative control group, the low dose group, the high dose group.
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