《环孢素a在肾内科的应用》专家协作组。
结论患者体重、年龄对环孢素a清除率有显著影响。
CONCLUSION Age and body weight influenced clearance of CsA in renal transplantation patients significantly.
结果：经小鼠皮肤给药，皮肤中环孢素A可达到有效药物浓度；
Results The effective concentrations of drug in the skin to treat psoriasis were obtained.
方法：采用HPLC测定小鼠皮肤中环孢素a的含量，光镜下观察其疗效。
Methods the drug concentrations in the skin were detected by HPLC method, and pharmacodynamics of anti psoriasis was observed by microscope.
目的以交联透明质酸为载体制备环孢素眼植入凝胶膜，观察其体外药物释放特性。
Primary study of characteristics and biocompatibility of the films made of cross-linked hyaluronic acid;
结果AG490能显著延长移植物存活时间，与环孢素a联用有协同效应，作用更强。
Results the AG490 prolonged the graft survival time almost equal to CsA, when used both AG490 and CsA the graft survival time has been prolonged more.
方法采用改良的乙醇注入结合超声分散的方法制备环孢素长循环脂质体，蔗糖作为冻干保护剂冻干。
METHODS Pegylated CsA-liposome was prepared by a modified ethanol injection method, followed by sonication and lyophilization using sucrose as cryoprotectant.
治疗方面，内用药物主要有抗肿瘤药物、环孢素A、维甲酸、抗菌药、生物制品、血管生成拮抗剂等。
On treatment, the oral medication mainly include anti-tumor drug, CyA, VA, anti-bacterium drug, biological products and blood vessel formation antigeon and so on.
方法：采用对照研究方法比较小剂量环孢素a和常规药物治疗CAA的疗效以及影响CS A疗效的因素。
Methods: a randomized control trial was employed to determine whether the outcome of CAA treated with low-dose CSA was better than that with routine drugs.
方法：采用对照研究方法比较小剂量环孢素a和常规药物治疗CAA的疗效以及影响CS A疗效的因素。
Methods: a randomized control trial was employed to determine whether the outcome of CAA treated with low-dose CSA was better than that with routine drugs.
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