探讨了呋喃酚环合反应质子酸催化机理。
The mechanism was discussed in the proton acid catalytic reaction of furan phenol cyclization.
所得公式可适用于多个环合点的热环合反应。
These formulae derived can be used to the ring formation with multi-points ring formation reactions.
本文主要研究手性模板作用下的光环合反应的立体选择性。
The aim of this research is to study the stereoselectivity of photocyclization reaction in the act of chiral template.
报导了杀鼠酮钠盐的用途及制备方法，并讨论了环合反应的最佳条件。
In this article, the process and preparation of valone are reported. Moreover, its best condition of linking reaction was also discussed.
环合反应的条件缓和，产品收率和纯度高，在四氢咔唑类化合物的化学制备中具有重要参考价值。
The conditions of reaction of cyclization were moderate, the purity and yield of the product was higher.
方法：通过付克反应、碳链延长、水解和环合反应得到两个关键中间体，然后通过酰化反应制得各种酰胺化合物；
METHODS: The title compounds were synthesized by acylation of twelve acyl chlorides and two intermediates prepared by Friedel Crafts reaction, lengthening of carbon chain, hydrolysis and cyclization;
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo-butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
筛选以2-溴代丁酸为起始原料，经氨解，酯化，酯胺解，拆分，环合五步反应制得左乙拉西坦。
Screening for 2 - bromo- butyric acid as the starting material, after ammonolysis, esterification, ester amine solution, split, five-step cyclization reaction Levetiracetam.
讨论了以草酸二乙酯为原料，经过克莱森缩合、环合、氨解反应合成5甲基异唑3甲酰胺工艺的改进。
This paper reports the improvement on the synthesis of 5 methylisoxazol 3 formamide by Claisen condensation of diethyl oxalacetate followed by cyclization and ammonolysis.
在此步反应中成功地以醋酸乙烯代替乙炔及其衍生物作为环合试剂进行了1,3 -偶极环加成反应，得到了目标产物。
With vinyl acetate as reactant in place of acetylene and its derivates in 1, 3 dipolar cycloaddition, the target product was obtained successfully.
用硫酸乙酐混合物作环合剂，制备了氟嗪酸中间体．该方法具有反应条件温和、价格便宜、后处理简单的优点，适用于工业化生产。
Sulfuric acid and acetic anhydride were used as a cyclizing agent to prepare Ofloxacin intermediate. The reaction could be carried out under moderate conditions and facilitate industrial produce.
方法采用对硝基苯胺为原料，经还原、加保护基、甲酰化、氯化、环合、脱保护基六步反应法可进行化学合成。
Methods Apraclonidine was synthesized from P-Nitraniline by reaction with reduction, adding protection group, formylation, chlorination, cyclization, off-protecting group.
同时对反应过程中的甲酰化、环合方法、反应时间进行了探讨，优化了反应条件，提高了产率，并对化合物的荧光光谱进行了分析。
Also the optimum reaction conditions including formylation, method and reaction time of cyclization were studied to enhance the yield. In the end, their fluorescence spectrum are analyzed.
以苯甲酰氯为原料，经酰化，还原，环合等反应合成左旋西替利嗪盐酸盐，反应总收率为8。05%。
Levocetirizine dihydrochloride was prepared from benzoyl chloride by acids lation hydrogenation cyclization with an overall yield of8.05%.
以苯甲酰氯为原料，经酰化，还原，环合等反应合成左旋西替利嗪盐酸盐，反应总收率为8.05%。
Levocetirizine Dihydrochloride was prepared from benzoyl chloride by acidylation, hydrogenation, cyclization with an overall yield of 8.05%.
研究了一种直接环合的方法，用2-氯-2氯甲基- 4-氰基丁醛与三氯氧磷反应来制备2-氯-5-氯甲基吡啶。
A synthetic method of direct cyclization was researched that 2-chloro-2-chloromethyl-4-cyanobutyraldehyde was reacted with phosphorus oxychloride to get 2-chloro-5-chloromethylpyridine.
方法以1，3-溴丙烷与乙酰乙酸乙酯为原料经环合、开环、溴代等反应合成。
METHODS The compound was synthesized through the reaction of cyclization, split, bromination et al and using 1,3-propyl bromide and ethyl acetoacetate as raw materials.
以对甲苯乙酮和三氟醋酸乙酯为原料，经缩合、环合两步反应得到2型环氧酶抑制剂赛来昔布，总收率为6 7%。
Celecoxib as a cyclooxygenase-2 inhibitor, was synthesized from p-methylacetophenone and ethyl trifluoroacetate by successively condensation and cyclization in 67% overall yield.
方法以苯乙胺为原料，经酰化反应得乙酰苯乙胺，在多聚磷酸的作用下环合得1-甲基-3，4-二氢异喹啉，经硼氢化钠还原得1-甲基-1，2，3，4-四氢异喹啉。
Methods 1-Methyl-1,2,3,4-tetrahydroisoquinoline was synthesized from phenethylamine through three steps:acetylation with acetyl chloride, cyclization with PPA and reduction with potassium borohydride.
方法以苯乙胺为原料，经酰化反应得乙酰苯乙胺，在多聚磷酸的作用下环合得1-甲基-3，4-二氢异喹啉，经硼氢化钠还原得1-甲基-1，2，3，4-四氢异喹啉。
Methods 1-Methyl-1,2,3,4-tetrahydroisoquinoline was synthesized from phenethylamine through three steps:acetylation with acetyl chloride, cyclization with PPA and reduction with potassium borohydride.
应用推荐