胜利似乎已经触手可及，但是这次他犯了重大的错误。
Victory appeared to be virtually guaranteed, but this time, Usain Bolt messed up on the big stage.
那个公司的总经理犯了一个重大的金融错误，被送进了监狱。
The general manager of the company made a grand financial mistake and was sent into prison.
尽管如此，美国指责欧洲正在失去土耳其的批评还是犯了把问题过于简单化的错误，忽视了对欧洲人而言土耳其加入欧盟是多么重大的一件事情这个事实。
For all that, American voices accusing Europe of losing Turkey are guilty of oversimplification, and of ignoring what a big deal Turkish membership of the EU would be.
相反，你应该“一直等着，直到你确信，你的老板犯了一个重大错误”——一个将危及他的既定目标的错误——“或者，直到你想出一个更好的主意，并且你对此信心满满。”
Instead, "wait until you're convinced your manager is making a huge mistake" — one that will jeopardize his own stated goals — "or until you come up with a better idea that you truly believe in."
他犯了重大判断失误的错误。
他犯了一个重大的错误。
经理犯了一个重大的判断错误。
经理犯了一个重大的判断错误。
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