寻找HCC特异性标志物一直是相关研究的热点。
目的:探讨蛋白指纹图谱技术筛选大肠癌(CRC)患者血清中可用于诊断的特异性标志物。
AIM: To screen the potential protein biomarkers in serum for the diagnosis of colorectal cancer (CRC) by the technique of proteomic fingerprint.
资料综合:骨髓基质干细胞具有多向分化能力,不具有特异性标志物,无法用某种特异性标志对其进行鉴定和分离。
DATA SYNTHESIS: The bone marrow mesenchymal stem cell had various ability of differentiation without specific sign, and could not evaluate and detach it with certain specific sign.
结果在白癜风白斑区表皮内,每100个表皮基底层细胞中MC平均数量为0,4种MC特异性标志物表达均为阴性。
Results in the depigmented macules of vitiligo, the average number of MC in every 100 basal layer cells was 0. No expressions of all the 4 MC specific markers were observed.
今后应加强与胆系恶性肿瘤相关疾病的监测和处理,并力求发现敏感性和特异性均高的肿瘤标志物,以发现早期肿瘤。
To diagnose the tumor in its early stage, the monitor and management of some diseases related to BMT should be enhanced, and tumor markers with high susceptibility and specificity should be explored.
《国际糖尿病》:氧化应激与糖尿病神经病变相关,是否有特异性的标志物评价抗氧化剂对糖尿病神经病变的作用?
International Diabetes: Oxidative stress is associated with the pathogenesis of diabetic neuropathy. Are there any specific markers to assess the benefits of antioxidants on diabetic neuropathy?
目的从胃癌患者胃液中发现特异性荧光物质,并以此来获得肿瘤标志物。
Objective to investigate some specific fluorescent substances in gastric juice from patients with gastric carcinoma and to establish biomarkers for the detection of gastric cancer.
结论多项肿瘤标志物联合检测可提高特异性,降低假阳性率。
Conclusion Joint detection of different tumor markers will increase the specificity of the immunoassay and lower its rate of false positivity.
与多项血清肿瘤标志物检测联合应用,能够进一步改善诊断的敏感性和特异性,提高早期诊断和鉴别诊断水平。
Combined with multiple serum tumor marker measurements, this method can improve diagnostic sensitivity and specificity, he nce it facilitates the early diagnosis and differential diagnosis.
结论采用C - 12系统检测乳管液肿瘤标志物的灵敏度明显高于血清,但特异性较差。
Conclusion By applying the C-12 system determination the tumor maker, the sensitivity of breast duct juice surpasses than in serum, but the specificity is not fine.
血清生化标志物凭借其特异性及敏感性,在AM I的早期诊断中具有重要的地位,现就国内外有关方面的实验研究报道作一综述。
Serum biochemical markers with their specificity and sensitivity play a significant role in the early diagnosis of AMI. We review the experimental studies at home and abroad concerning this topic.
结论:应用rt - P CR法以CK20为标志物检测胃癌微转移细胞特异性高。
Conclusion: Using CK20 mRNA as a marker, the detection of micrometastasis with RT-PCR technique shows favorable specificity.
结论:ND- 1对人结肠癌患者血清具有较好的特异性,是具有应用价值的新型血清标志物。
Conclusions: nd 1 has a good specificity to the serodiagnosis of colorectal cancer patients and is a new serum mark that has value of application.
随着研究的不断深入,RUNX3基因有望成为胃癌诊断的一个特异性生物学标志物和基因治疗的靶点。
Along with the thorough research, RUNX3 may be a potential marker in the diagnosis and gene treatment of gastric cancer.
结论TRFIA技术检测HBV血清标志物灵敏度高、特异性强,可替代MEIA和ELISA而成为一种常规检测方法。
Conclusion To detect HBV markers in serum, TRFIA offers many benefits in sensitivity, specificity, accuracy and practicability, and may be a routine method instead of MEIA and ELISA.
虽然当前血清cea和CA- 199等的检测已被广泛应用于大肠癌的筛选,但其缺乏特异性和敏感性,这就需要进一步寻找新的标志物。
Current biomarkers (such as CEA and CA-199) lack sensitivity and specificity for general population screening. Hence, there is a great need for new biomarkers for early detection of CRC.
临床上需要一些早期即可以测量的、敏感的、特异性的标志物来诊断疾病。
The measurable, sensitive and specific biomarkers, which can be detected in the early stage of disease, are very necessary for the diagnosis in clinics.
《国际肝病》:就生物学标志物而言,我们仍在努力发现候选的特异性肝癌标志物。
Hepatology Digest: in terms of biomarkers we are still struggling to find specific candidates for this cancer.
目的:研究遗传印记基因PEG10在肝癌组织中表达的特异性,及在不同肿瘤细胞中的表达情况,为其作为一个潜在的肝癌特异标志物和HCC基因治疗的新的分子靶点提供实验依据。
AIM: To study the specificity of the expression of PEG10 in HCC tissues and evaluate the feasibility for PEG10 as a novel molecular target of gene therapy for HCC.
结论:PA对人类恶性肿瘤缺乏特异性,但可作为鉴别卵巢良、恶性病变的有价值标志物。
Conclusions 1. PA lacks the specificity for diagnosis of human malignancies, however, it would be used as a tumor marker to differentiate ovarian cancers from women with benign pelvic masses.
这些多肽序列在肿瘤血管靶向治疗,肿瘤血管特异性分子标志物试剂的研制方面将具有巨大的潜在价值。
These polypeptide sequences have great potential in the targeting treatment of tumor veins and the development of the symbol reagent of the specific molecule of the tumor veins.
这些多肽序列在肿瘤血管靶向治疗,肿瘤血管特异性分子标志物试剂的研制方面将具有巨大的潜在价值。
These polypeptide sequences have great potential in the targeting treatment of tumor veins and the development of the symbol reagent of the specific molecule of the tumor veins.
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