下面就第三期牙本质基质的形成过程作一综述。
This review focused on the process of production of tertiary dentin matrix.
目的：克隆人牙本质基质蛋白1 (DMP1)成熟肽编码区基因片段。
Aim: Cloning and partially sequencing of human dentin matrix protein 1 (DMP1) encoding mature protein.
随后其表达随细胞分化的成熟和牙釉质、牙本质基质形成的进展而逐渐下降。
The expression was down-regulated with enamel and dentin matrix formation being up - regulated.
依据第三期牙本质基质的来源可进一步将其分为反应性牙本质和修复性牙本质。
According to the origin of tertiary dentin matrix, it may be subdivided into reactive dentin and reparative dentin.
下面就牙本质基质蛋白- 1的表达定位、基因结构、生物学功能以及表达调控因素作一综述。
The expression orientation, gene structure, biological function and regulation of dentin matrix protein-1 in dentin and bone was reviewed in this paper.
牙本质基质蛋白(DMP)- 1是骨、软骨、釉质、牙骨质和牙本质生物矿化所必需的一种酸性非胶原蛋白。
Dentin matrix protein (DMP) -1 is an acidic non-collagenous protein that is necessary for the proper biomineralization of bone, cartilage, cementum, dentin and enamel.
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage.
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage. A high level of MMP-2 was confined to secretory odontoblas…
结果：牙胚发育过程中的蕾状期、帽状期、钟状晚期基质金属蛋白酶- 2 （MMP - 2 ）均有表达，但以钟状期前牙本质细胞的表达最明显。
RESULTS: The expression of MMP-2 could be found in bud stage , cap stage and later time of bell stage. A high level of MMP-2 was confined to secretory odontoblas…
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