结论亚低温对缺血脑组织具有保护作用,对炎症级联反应的抑制可能是其发挥脑保护作用的重要机制之一。
Conclusion Mild hypothermia has a protective role in cerebral ischemic tissue and inhibits the inflammatory cascade reaction, which may be one of the neuroprotective role mechanisms.
当合胞体滋养层细胞死亡,他们就会释放到母体的血液循环中,从而引起炎症级联反应,进而损害母体的器官。
When syncytiotrophoblast cells die, they are released into the maternal circulation, initiating a cascade of inflammation that can damage maternal organs.
RAS抑制可以通过多种分子机制抑制肺泡上皮细胞和血管内皮细胞的凋亡,抑制炎症级联反应和细胞外基质沉积,而使肺纤维化病变减轻。
RAS inhibition can reduce cell apoptosis of alveolar epithelial cells and endothelial cells, interfere with the inflammation cascade, and decrease fibroblast activity during tissue repair process.
结论甘露醇可能通过影响炎症损伤级联反应的多个环节,抑制CEC、IL - 8等多种效应因子的产生和表达,从而对ALI发挥防治作用。
Conclusion Mannitol has a protective effect on rabbits with ALI through effecting various cascade reaction of inflammatory injury and down regulating of the generation and expression of CEC and IL-8.
这些炎症小体联合起来可以激活半胱天冬酶- 1,这种蛋白依次激活炎症的级联反应。
The inflammasomes join together and activate a protein, caspase-1, that in turn triggers an inflammatory response.
另外,许多炎性因子可激活ICAM - 1蛋白表达,导致炎症的级联反应。
In addition, a great deal of inflammatory factors can activate the expression of ICAM-1 protein and lead to inflammatory cascade reaction.
更多需要了解的问题是有关凝血酶多重功能的作用,凝血酶是血凝级联反应的终酶,同时也具有诱发炎症反应的作用。
More problematic is the multifunctional role of thrombin, the terminal enzyme in the coagulation cascade, which is also capable of stimulating an inflammatory response.
脑缺血后星形胶质细胞作为中枢神经系统第一个受损的细胞,出现肥大、增殖,并合成表达多种炎症介质,启动免疫级联反应。
Then ischemia stimulates hypertrophic and proliferative changes in astroglia and induces it produce inflammatory factors involved in the initiation of immunologic cascade.
脑缺血后星形胶质细胞作为中枢神经系统第一个受损的细胞,出现肥大、增殖,并合成表达多种炎症介质,启动免疫级联反应。
Then ischemia stimulates hypertrophic and proliferative changes in astroglia and induces it produce inflammatory factors involved in the initiation of immunologic cascade.
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