一些青少年已经转换了一个特定的基因——糖皮质激素受体(GR)——帮助调节体内荷尔蒙对于压力的反应。
Some of the teens had changed to one particular gene—the glucocorticoid receptor (GR)—that helps regulate the body's hormonal response to stress.
我们现正研究对雌激素受体,或内质网。
雌激素受体;孕激素受体;浆液性卵巢癌。
Estrogen receptor; Progesterone receptor; Serous cystadenocarcinoma of the ovary.
而没有雌激素受体的雄性老鼠的无名指则更长。
Male mice without estrogen receptors had longer ring digits.
研究者们进一步探究是什么造成了糖皮质激素受体基因表达的差异。
The researchers went on to study what is responsible for the difference in expression of the glucocorticoid-receptor gene.
这就可以解释为什么两组老鼠中的糖皮质激素受体蛋白水平会有差异。
This explains why levels of glucocorticoid-receptor protein are different in the two groups of rats.
在卵巢的内分泌调控中,雌激素受体发挥着重要的生理作用。
Estrogen Receptor play key role in the endocrine regulation of ovary.
确定这些细胞雌激素与孕激素受体阳性与否对治疗与预后也很重要。
It would also be important for treatment and prognosis to determine if these cells were estrogen and progesterone receptor positive.
大鼠脑缺血急性期脑甲状腺激素受体向上调节为机体的重要代偿反应。
The results indicated the upward regulation of TR in rat brain during acute cerebral ischemia is a compensatory response, which allows the maximum binding of thyroid hormones.
主题演讲将突出集成斑块脂质代谢和免疫活性的核激素受体的新兴角色。
The keynote address will highlight emerging roles of nuclear hormone receptors as integrators of plaque lipid metabolism and immune activity.
结果:Y染色体上的一些基因、雄性激素受体基因等被证实与生精障碍相关。
Results: some genes including several genes on Y chromosome and androgen receptor gene were demonstrated to be associated with spermatogenesis impairment.
长生奖的得主则是一只无法合成生长激素受体分子的老鼠——其体型与一般老鼠并无二致。
The longevity prize is held by an animal that could not make the receptor molecule for growth hormone and was thus a fraction of the size of normal mice.
如果,相同的补充,你可以放大你的肌肉的雄激素受体切换的能力对肌肉增长?
What if, with the same supplement, you could amplify your muscle's androgen receptors ability to switch on muscle growth?
同时,Young博士说他和同事已经发现人类抗利尿激素受体基因的许多变异。
Meanwhile, Dr Young says that he and his colleagues have found a lot of variation in the vasopressin-receptor gene in humans.
例如,糖皮质激素受体基因在大脑特定区域的持续表达提高了调节应激反应的能力。
For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.
没有雄激素受体对雄激素发生反应,研究者开始想到雄激素受体并非他们原来想象得那样起作用。
Without male hormone receptors to respond to testosterone, the researchers started to suspect androgen receptors were not the players they had been assumed to be.
根据这项新的研究,的确,对雌激素受体阳性肿瘤和雌激素受体阴性肿瘤的妇女都有利。
According to this new study, yes, it is beneficial to both women who have estrogen receptor positive tumors and estrogen receptor negative tumors.
当它与其它组织如生殖系统组织中的雌激素受体结合时,对与生殖相关的功能没有影响。
When it binds to estrogen receptors in other tissues, such as reproductive tissues, it has no effect on their reproduction-related functions.
研究大脑其他区域的雌激素受体增加所带来的影响对弄清记忆处理的某些过程有所帮助。
Studying the effects of increasing the estrogen receptor in other brain regions may shed additional light on memory processes.
当研究人员改变早先的原始受体的这7个位点后,它就成为了一个新的糖皮质激素受体了。
When he made these 7 changes to the ancestral receptor, it behaved just like a new glucocorticoid receptor.
研究发现,孕期中遭到虐待的母亲生下糖皮质激素受体基因被甲基化的幼儿的可能性要比其他母亲高出得多。
They found that women abused during pregnancy were significantly more likely than others to have a child with methylated glucocorticoid-receptor genes.
而缺少雌激素受体的雌性老鼠生来指爪就更长,那些没有雄激素老鼠的指爪则更短,并且非常女性化。
Female mice that lacked an estrogen receptor were born with longer digits, and those that did not have testosterone had shorter, superfeminine digits.
在治疗的第3年,雌激素受体阳性患者获得97%的无远处复发生存率,绝对危险度大幅下降11%。
At 3 years, ER-positive patients achieved a DRFS of 97% and a significant absolute risk reduction of 11%.
他们的团队对一组10到19岁的儿童进行了糖皮质激素受体基因甲基化的检测,并对他们的妈妈做了同样的检测。
Their team examined the methylation of the glucocorticoid-receptor gene in a group of children ranging in age from ten to 19 years, and in those children's mothers.
在此模型中,更高的临床肿瘤分级及雌激素受体阴性与远处复发或死亡存在具有显著统计学差异的相关性。
In this model, higher clinical tumor stage and ER-negative status were associated with a statistically significantly greater risk for distant relapse or death.
日前,约翰·霍普金斯的研究者发现在内分泌治疗无反应的患者的前列腺癌细胞的激素受体存在明显的差异。
Now, researchers at Johns Hopkins have discovered critical differences in the hormone receptors on prostate cancer cells in patients who no longer respond to this therapy.
研究者在一段时间内训练小鼠找出一个隐藏到微型游泳槽内的平板,缺乏雌激素受体的小鼠的学习能力很差。
Mice that lacked the estrogen receptor showed poor ability to locate a platform hidden in a small swimming tank over a training period of several days.
研究者在一段时间内训练小鼠找出一个隐藏到微型游泳槽内的平板,缺乏雌激素受体的小鼠的学习能力很差。
Mice that lacked the estrogen receptor showed poor ability to locate a platform hidden in a small swimming tank over a training period of several days.
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