目的克隆激活转录因子(atf)5，构建其真核表达载体，观察其在细胞中的表达定位。
Objective to clone the gene activating transcription factor 5 (ATF5), construct the expression plasmid and detect the localization of ATF5 in cultivated cells.
这一新研究领域依赖于获得被称作转录因子的主蛋白质，这种蛋白质控制细胞中哪组基因被激活，从而也就控制了细胞拥有哪些特性。
The new field depends on capturing master proteins called transcription factors that control which sets of genes are active in a cell and thus what properties the cell will possess.
转录辅激活蛋白和其他细胞因子及结构共同作用控制基因活动。
Transcriptional coactivators work with other cellular factors and machinery to control the activity of other genes.
IRF 4是IRF转录因子家族之一，在免疫细胞上表达，并从不同受体途径激活或抑制基因传导信号。
IRF4, a member of the IRF family of transcription factors, is expressed in cells of the immune system where it transducers signals from various receptors to activate or repress gene expression.
活跃的cyclinD/CDK4复合体靶向视网膜母细胞瘤蛋白以利于磷酸化，促进可以激活G1/S期基因表达的转录因子E2F的释放（3）。
The active complex of cyclin D/CDK4 targets the retinoblastoma protein for phosphorylation, allowing the release of E2F transcription factors that activate G1/S-phase gene expression (3).
目的研究MTS1基因arf启动子基础转录调控区的转录激活及其与E2 F1转录因子之间的关系。
Objective to study the effect of E2F1 transcription factor on the transcriptional activity of basic transcriptional regulatory region in the ARF promoter of MTS1 gene.
热休克因子1 (HSF1)是一种转录因子，在正常时不活化，应激时活化而具有反式激活能力。
As a transcription factor, heat shock transcription factor 1 (HSF1) is activated during stress and subsequently trans-activate its downstream factors.
Ricci指出：“激活后，这几千种不同的转录因子即与其DNA序列特定靶标相结合。”
"Upon activation, these thousands of different transcription factors bind to their own specific target DNA sequence," said Ricci.
在正常生长条件下，热激因子处于钝化的单体状态，而当热激时，热激因子形成三聚体并与DNA结合，同时通过转录激活域的活化而激活热激基因的表达。
HSF is present in a latent state under normal conditions; it is activated upon heat stress by induction of trimerization, high affinity binding to DNA and transcriptional activity.
提示面神经损伤后面神经核运动神经元内由信号转导子和转录激活子3介导的细胞因子的信号转导作用增加。
Action of signal transduction of mediated cytokine indicated by STAT3 raises in motoneurons of facial nerve nucleus after facial nerve injury.
现有研究证明，与转录因子活力有关联的是转录辅激活子，它能增强转录因子和顺式作用元件的结合。
It has been demonstrated that transcriptional coactivator has close relationship with transcriptional factors and can enhance the combination of transcriptional factors and cis-acting element.
目的：检测银屑病信号转导和转录激活因子-3（PSTAT3）和血管内皮生长因子（VEGF）在寻常型银屑病皮损中的表达。
Objective: To investigate the expression of PSTAT3 and vascular endothelial growth factor (VEGF) in psoriasis vulgaris and their relationship.
甲状腺器官形态形成早期阶段，某些转录因子通过激活甲状腺特异基因的转录，对甲状腺细胞迁移、增殖与分化起重要作用。
Genes involved at early stage of the morphogenesis play important roles in thyroid cell migration, proliferation and differentiation by activating thyroid-specific gene transcription.
CD 4 +T细胞被激活时，较少的转录因子启动了较多的基因。
In activation of CD4 + t cell, less transcription factors regulate more genes.
缺氧诱导因子- 1 (HIF - 1)是由低氧等诱导细胞产生的1种转录因子，能激活许多缺氧反应性基因的表达。
Hypoxia inducible factor-l (HIF-1), which can stimulate expression of hypoxia induced-responsed, is a kind of transcriptive factor.
缺氧诱导因子- 1 (HIF - 1)是由低氧等诱导细胞产生的1种转录因子，能激活许多缺氧反应性基因的表达。
Hypoxia inducible factor-l (HIF-1), which can stimulate expression of hypoxia induced-responsed, is a kind of transcriptive factor.
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