本文讨论了1-溴代金刚烷的合成，为工业化生产金刚烷胺盐酸盐提供了资料和数据。
The paper discusses the synthesis of 1-bromoadamantane, providing materials and data for the industrial production of adamantanamine hydrochloride.
以1，3-二甲基金刚烷为原料，经溴化、乙腈和硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚，总收率6 7。8%。
Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%.
以1，3-二甲基金刚烷为原料，经溴化、乙腈和硫酸的作用下乙酰胺基化、水解、成盐等反应及改进的后处理方法得到盐酸美金刚，总收率6 7。8%。
Memantine hydrochloride was synthesized from 1,3 dimethyladamantane by bromination, acetamidation with acetonitrile in sulfuric acid and hydrolysis with an overall yield of 67.8%.
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