以对甲酚为原料经溴化、水解、甲氧基化和甲基化4步反应合成药物中间体3,4,5-三甲氧基苯甲醛,总收率达53。
The 3,4,5 trimethoxybenzaldehyde is synthesized from p cresol in four steps of bromination, hydrolyzation, methoxylation, and methylation, with an overall yield of 53.
以愈创木酚为起始原料,采用各种不同的催化剂与溴苯缩合制备得到邻甲氧基二苯醚,并研究了碱、催化剂、反应温度、反应时间和加料方式各种因素对该反应的影响。
Methoxydiphenyl ether was synthesized from guaiacol by using various catalysts and bases. The influences of base, catalyst, temperature, time and the way of feeding on the reaction were studied.
以愈创木酚为起始原料,采用各种不同的催化剂与溴苯缩合制备得到邻甲氧基二苯醚,并研究了碱、催化剂、反应温度、反应时间和加料方式各种因素对该反应的影响。
Methoxydiphenyl ether was synthesized from guaiacol by using various catalysts and bases. The influences of base, catalyst, temperature, time and the way of feeding on the reaction were studied.
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