另外五百万克朗则颁发给了来自加拿大的拉尔夫·斯坦曼·斯坦曼发现了能够起到激活免疫系统主要细胞大军(即t淋巴细胞)功能的树突细胞。
The other 5m crowns went to Ralph Steinman, from Canada, who discovered the role of dendritic cells in activating some of the immune system's main cellular troops, known at T-lymphocytes.
正常的树突状细胞会把异源体递呈给T细胞使其产生杀伤性T淋巴细胞来摧毁它。
Normally dendritic cells show an invader to T cells which produce cytotoxic T cells to destroy it.
结论:人类滤泡树突状细胞能够增强HIV在淋巴细胞中的感染,其相关机制为FDC可促进HIV在淋巴细胞内的复制。
Conclusion: Human follicular dendritic cells can increase HIV infection in lymphocytes and the possible related mechanism is that FDC may promote HIV replication in lymphocytes.
目的探讨淋巴结滤泡树突状细胞肉瘤的临床和病理特点。
Objective To investigate the clinical and pathologic characteristics of the follicular dendrite cell sarcoma of lymph node.
目的探讨淋巴结原发性指突状树突细胞肉瘤的临床病理特点及鉴别诊断,提高对该肿瘤的诊断水平。
Objective To investigate the clinical pathological features and differential diagnosis of interdigitating dentrtic cell sarcoma(IDCS) to improve diagnostic level of it.
树突状细胞与乳腺癌的组织类型,腋窝淋巴结转移状况及癌周淋巴细胞及浆细胞的浸润程度有关。
Such dendritic cell was related to histologic classification of breast carcinoma, metastases in lymph node and the intensity of lymphocyte and plasma cell infiltration around the carcinoma.
目的:探讨致敏的树突状细胞(DC)激活的肿瘤浸润淋巴细胞(TIL)体外抗小鼠乳腺癌活性。
Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.
透射电镜观察表明,棉铃虫触角上起嗅觉作用的毛形感器和锥形感器均由表皮壁、鞘细胞、感受器淋巴液和感觉神经细胞树突等结构组成。
Sensillum trichodeum and sensillum basiconicum, the main chemical odor receptors on antennae of Helicoverpa armigera, consist of cuticular wall, sheath cells, sensillum lymph and dendrites.
目的研究负载肿瘤抗原的树突细胞能否诱导特异性细胞毒t淋巴细胞反应。
Objective to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma patients.
结论:得到了一群较高程度表达CD 83、CD 86和HLA - DR分子、体外可强烈激发同种异体t淋巴细胞增殖的树突状细胞群。
CONCLUSION: a group of dendritic cells, which highly express CD83, CD86 and HLA-DR molecules, and stimulate strongly allogeneic t lymphocyte proliferation in vitro, are obtained.
目的研究MAGE-A3抗原肽负载对乳腺癌患者树突状细胞(DC)的功能的影响,探讨其是否可以在体外诱导特异性细胞毒性T淋巴细胞(CTL)应答。
Objectve: To investigate whether the dendritic cells(DCs) loaded with the peptide derived from MAGE-A3 could induce specific cytotoxic T lymphocytes(CTLs) response in breast cancer patients in vitro.
目的:探讨负载肿瘤抗原的树突状细胞(DC)疫苗诱导的细胞毒性T淋巴细胞(CTL)的体外杀瘤作用及对荷瘤小鼠的治疗作用。
Objective: to explore the anti-tumor effects of cytotoxic of T-lymphocytes (CTL) induced by dendritic cells (DC) vaccine loaded with tumor antigen.
结果表明:乳腺癌组织中散在分布S100蛋白阳性的树突状细胞,而癌周及癌旁的淋巴细胞及浆细胞密集区可见树突状细胞成簇存在。
The result showed that S100 protein positive dendritic cells distributed sparsely in malignant cells and formed a cluster among lymph cells and plasma cells.
目的:研究多发性骨髓瘤(MM)患者肿瘤冻融物致敏的树突细胞(DC)能否诱导特异性细胞毒t淋巴细胞(CTL)反应。
Objective: to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma (MM) patients.
结果IL-2活化培养7d后肿瘤浸润树突细胞(TIDC)和肿瘤浸润T淋巴细胞(TIL)数量明显增加(P<0.01)。
Results After activated by IL-2 for 7 days, the number of tumor infiltrating dendritic cells(TIDC) and tumor infiltrating T lymphocytes(TIL) were increased(P<0.01).
再将RB肿瘤抗原致敏树突状细胞,与自体淋巴细胞共孵育后,能诱导出特异性杀伤肿瘤细胞的CTL。
The dendritic cells were induced by RB tumor antigen and then it cooperated with RB tumor lysates in vitro to induce antigen specific CTL which can kill the SO-RB50 target cells specifically.
再将RB肿瘤抗原致敏树突状细胞,与自体淋巴细胞共孵育后,能诱导出特异性杀伤肿瘤细胞的CTL。
The dendritic cells were induced by RB tumor antigen and then it cooperated with RB tumor lysates in vitro to induce antigen specific CTL which can kill the SO-RB50 target cells specifically.
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