我们现在认为可能并不是淀粉样纤维细丝导致神经元死亡和疾病的发作。
We now think that it may not be the amyloid fiber filaments that cause neuron death and disease onset.
这里的淀粉样纤维蛋白是特定的Afp而且与前白蛋白有化学上的关联。
Here the amyloid fibril protein is designated AFp and appears to be chemically related to prealbumin.
目的:研究氨基酸对牛胰岛素淀粉样纤维的生成、形态和细胞毒性的影响。
AIM: to investigate the effect of amino acids on the formation, morphology and cytotoxicity of amyloid fibril of bovine insulin.
阐明淀粉样纤维的毒性机制对于研制用于治疗淀粉样疾病的药物显得异常重要。
It is essential to elucidate the cytotoxic mechanism of amyloid fibrils for developing novel medicines for the treatment of amyloid diseases.
通常情况下,淀粉样纤维在靶细胞的附近沉积,在细胞膜上聚集,引起细胞的连锁反应而导致细胞的死亡。
Usually amyloid fibrils form and deposit in the vicinity of the target cells and accumulate on the cell membrane, triggering a cascade of cellular events which lead to apoptosis.
为此我们得出结论:高分子量蛋白如bsa也能形成淀粉样纤维,但是BSA形成的淀粉样纤维主要因为其表面疏水性较低使其没有细胞毒性。
We concluded that a protein with high molecular weight such as BSA can also form amyloid fibrils, although the resultant amyloids showed no cytotoxicity due mainly to their low surface hydrophobicity.
电子显微镜能显示出淀粉样蛋白纤维的特征,在早期的病例中这项技术有时是诊断所必需的。
Electron microscopy reveals the characteristic fibrils of amyloid and in early cases this technique is occasionally essential for the diagnosis to be made.
目的研究胶质纤维酸性蛋白(GFAP)在淀粉样脑血管病(CAA)患者脑组织的表达。
Objective To investigate the expression of glial fibrillary acidic protein(GFAP) in brains of patients with cerebral amyloid angiopathy(CAA) related to hemorrhage.
本周蛋白在体外的酶消化过程显示典型的具有β-折叠片结构的淀粉样蛋白纤维能通过一些,但不是全部的,本周蛋白生成。
Enzymatic digestion of Bence Jones proteins in vitro has shown that typical amyloid fibrils with a beta-pleated sheet configuration can be formed from some, but not all, Bence Jones proteins.
电镜,淀粉样物质是由原纤维的β-折叠组成。可见不规则的灰色物质。
By electron microscopy, amyloid is composed of a "beta-pleated sheet" of fibrils, seen here as irregular grey material.
电镜,淀粉样物质是由原纤维的β-折叠组成。可见不规则的灰色物质。
By electron microscopy, amyloid is composed of a "beta-pleated sheet" of fibrils, seen here as irregular grey material.
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