近年来研究发现，蛋白质的错误折叠可以形成淀粉样沉积进而导致一些疾病的产生。
In recent years, a number of diseases are believed to be caused by amyloid deposition results from protein misfolding.
在同一个10年中，杰出的化学家Kekule证明了淀粉样沉积物的蛋白质本质。
In that same decade, the distinguished chemist Kekule demonstrated the proteinaceous nature of amyloid deposits.
在其他类型的淀粉样变患者罕见获得性止血缺陷，已报道淀粉样沉积为异常出血表现的主要原因。
In patients with other types of amyloidosis, acquired hemostatic defects are rare, and amyloid deposition has also been reported to be the main cause of abnormal bleeding manifestations.
这可能是因为淀粉样沉积的只对小部分患者例如骨髓瘤患者具有易感性这一显而易见的缺陷造成的。
This may account for the apparent limitation of susceptibility to amyloid deposition to only a relatively small percentage of patients with, for instance, myelomatosis.
淀粉样变的严重性依赖于淀粉样蛋白沉积在哪个器官。
The severity of amyloidosis depends on which organs the amyloid deposits affect.
这个样本会送往实验室在显微镜下检查是否有淀粉样蛋白沉积。
The sample is then examined under a microscope in a laboratory to check for signs of amyloid.
淀粉样蛋白通常由骨髓细胞合成，可以在各个组织和器官中沉积。
Amyloid is an abnormal protein usually produced by cells in your bone marrow that can be deposited in any tissue or organ.
这种疾病的众多隐秘信号之一是在脑中的B -淀粉样蛋白斑块中的沉积。
One of the telltale signs of this disease is the deposit of beta-amyloid plaques in the brain.
她的团队已经在早期做了大量的工作，至少在小鼠中，疱疹病毒感染的神经细胞导致了beta-淀粉的沉积，而这是淀粉样蛋白斑块的主要成分。
Earlier work done by her team has shown that, in mice at least, the herpes infection of nerve cells induces accumulation of beta amyloid, the main component of amyloid plaques.
刚果红染色，在偏振光下观察，如图所见在心脏一动脉周围的沉积物，淀粉样物质呈现典型的“苹果绿”双折射光。
When stained with Congo red and observed under polarized light, the amyloid has a characteristic "apple green" birefringence as seen here in a deposit around an artery in the heart.
结果显示颞叶下皮质淀粉样蛋白沉积量的增加影响了与海马之间的联系，进而导致神经元的死亡。
The results indicate that the increased accumulation of amyloid in the temporal inferior cortex disrupts connections with the hippocampus, causing the neurons to die.
胰岛淀粉样蛋白沉积是2型糖尿病的重要特征之一。
Islet amyloid is one of the important characteristics of type 2 diabetes.
在胰岛的胰腺细胞内可见粉红色的透明变性（淀粉样物质沉积）。
This islet of Langerhans demonstrates pink hyalinization (with deposition of amyloid) in many of the islet cells.
通常情况下，淀粉样纤维在靶细胞的附近沉积，在细胞膜上聚集，引起细胞的连锁反应而导致细胞的死亡。
Usually amyloid fibrils form and deposit in the vicinity of the target cells and accumulate on the cell membrane, triggering a cascade of cellular events which lead to apoptosis.
在19世纪50年代早期，Virchow被淀粉样蛋白的组织沉积表现所启发提出了淀粉样蛋白具有多糖的成分。
In the early 1850's Virchow was led by the appearance of the tissue deposits of amyloid to suggest that it had a polysaccharide composition.
Tramiprosate旨在防止淀粉样蛋白在大脑中形成和沉积，从而修改反倾销过程。
Tramiprosate was designed to prevent amyloid formation and deposition in the brain, and thus modify the course of AD.
本发明还公开了上述化合物在检测或显像动物、人体或组织内淀粉样蛋白沉积中的应用。
The invention also discloses an application of the novel compounds in detecting or imaging amyloid deposition in animals, human or tissues.
线虫不表达内源性B淀粉样蛋白（A，这种蛋白是一种齐聚和形成AD大脑沉积物的肽。
Nematodes do not express endogenous B amyloid (A, the peptide that oligomerizes and form deposits in AD brains.
描述了一种用于在任何临床状况下抑制对象中的淀粉样蛋白沉积的治疗制剂和方法。
Therapeutic formulations and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described.
描述了一种用于在任何临床状况下抑制对象中的淀粉样蛋白沉积的治疗制剂和方法。
Therapeutic formulations and methods for inhibiting amyloid deposition in a subject, whatever its clinical setting, are described.
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