提到生物催化,我们通常会想到外消旋物的动力学拆分和手性合成。
When considering biocatalysis, terms like kinetic racemic resolution or chiral syntheses immediately come to mind.
外消旋体的动力学拆分反应是制备手性化合物的重要方法之一。
The kinetic resolution of raceme is one of the important ways in the synthesis of chiral compounds.
固体消旋蛋氨酸(DLM)和蛋氨酸羟基类似物自由酸(MHA - FA)是两种常用的蛋氨酸添加剂。
Solid racemated methionine (DLM) and methionine hydroxy analogue free acid (MHA-FA) are two usual methionine additives.
利用外消旋体进行化学-酶催化动态动力学拆分是制备单一手性化合物的有效手段之一。
The chemoenzymatic dynamic kinetic resolution(DKR) of racemates is one of the efficient ways in the preparation of single chiral compounds.
目前,用于拆分外消旋化合物的酶多数是水解酶,而且绝大多数为脂肪酶。
Presently, most of the catalysts used for the resolution of racemic mixtures are hydrolases, especially lipases.
综述了手性包结拆分方法在拆分外消旋化合物中的应用,并讨论了包结拆分中的手性识别原理。参考文献47篇。
The resolution of racemic compounds by crural inclusion complexation reported in 47 references is reviewed with 47 references. The chiral recognition principles in inclusion complex is also discussed.
从螺旋理论看,芳香轮烯和非芳香轮烯都是内消旋体和外消旋体的混合物,故都不呈现旋光性。
In the light of the helix theory, aromatic annulenes and non-aromatic annulcncs are all the mixture of the mesomer and raceme, so they haven't opticity activeity.
将所得聚合物用作高效液相色谱固定相,研究了它们对外消旋卡尼丁盐酸盐的拆分能力。
The prepared polymers were applied as the liquid chromatographic chiral stationary phase to test their resolution ability for racemic carnitine hydrochloride.
外消旋体拆分是获得单一手性化合物的重要途径。
Raceme separation is the main rout for preparation of pure enantiomers.
聚合物作为高效液相色谱的固定相,消旋体酮洛芬在固定相能分开,同时聚合物还能将酮洛芬和布洛芬的混合物分开。
Racemic ketoprofen was separated when the polymer was used as a stationary phase of high performance liquid chromatography. The mixture of ketoprofen and ibuprofen were also separated by this polymer.
以有机碱为催化剂 ,通过三唑三甲基丙酮与2 ,4-二氯苯甲醛的反应 ,合成了具有生物活性的外消旋体化合物烯唑醇。
By using alkalamides as the catalyst, diniconazole has been synthesized by the reaction of triazolyl-trimethylacetone and 2,4-dichlorobenzaldehyde.
以有机碱为催化剂 ,通过三唑三甲基丙酮与2 ,4-二氯苯甲醛的反应 ,合成了具有生物活性的外消旋体化合物烯唑醇。
By using alkalamides as the catalyst, diniconazole has been synthesized by the reaction of triazolyl-trimethylacetone and 2,4-dichlorobenzaldehyde.
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