结论切断穹窿海马伞可引起动物学习记忆障碍。
Conclusion Fimbria fornix transection lesion can results in rats learning and memory disorder.
吞噬样细胞数量最多,主要位于海马伞的多纤毛区;
The number of phagocyte-like cells that mainly existed on the ciliated surface of hippocampal fimbria was the most;
目的:观察横断大鼠穹窿-海马伞对其海马突触形态的影响。
Aim: To observe the effect of fimbria-fornix (ff) transection on rats hippocampal synaptic configuration.
双侧穹窿海马伞对照组仅切断双侧穹窿海马伞浅层的皮质组织。
In FF control, the cortical tissue of the superficial layer of bilateral fimbria-fornix was transectioned.
结果(1)大鼠海马伞的室管膜表面覆盖着大量的纤毛和微绒毛;
Results (1) A lot of cilia and microvilli were obversed on the surface of hippocampal fimbria.
方法采用损伤穹隆—海马伞的方法造成胆碱能系统损害学习记忆障碍痴呆模型。
Method: the senile dementia model with learning-memory disorders was built by cutting off the fornix-fimbria hippocampi to damage the cholinergic system.
室管膜上神经纤维可存在于海马伞的多纤毛区,也可存在于海马体的少纤毛区。
Supraependymal nerve fibers existed not only on the ciliated surface of hippocampal fimbria, but also in the middle and posterior surfaces of hippocampal body.
结论:穹窿海马伞切断ad大鼠海马erk升高,说明erk信号转导途径在AD发病早期有改变。
Conclusion: the level of ERK increased in hippocampus of rat model of AD, which showed changes of signal transduction route in the early phase.
结论:穹窿海马伞切断ad大鼠海马erk升高,说明erk信号转导途径在AD发病早期有改变。
Conclusion: the level of ERK increased in hippocampus of rat model of AD, which showed changes of signal transduction route in the early phase.
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