越来越多的研究表明了这种蛋白与蛋白酶体——细胞内蛋白酶机械，特别是泛素-蛋白酶体的相关性。
Increasing evidence has identified a correlation between this protein and the proteasome, the cellular proteolytic machinery, in particular the ubiquitin-proteasome system.
目的探讨泛素-蛋白酶体通路(UPP)在实验性视网膜脱离(RD)中对视网膜细胞凋亡的调控作用。
Objective to investigate the role of ubiquitin-proteasome pathway (UPP) in the regulation of retinal cell apoptosis after experimental retinal detachment (RD).
现就泛素-蛋白酶体系统与心肌再灌注损伤的关系以及抑制蛋白酶体的活性后对心肌再灌注损伤的影响进行综述。
Here, the relationship between UPS and myocardial reperfusion injury and the influence of proteasome inhibitor to myocardial reperfusion injury are reviewed.
CHIP的特殊结构特征使其成为沟通分子伴侣与泛素-蛋白酶体通路之间的桥梁，是蛋白质量控制系统的重要中介分子。
The special characteristics of CHIP make it become the bridge of molecular chaperone system and ubiquitin-proteasome pathway.
目的：研究泛素蛋白酶体抑制剂对胃癌细胞增殖和凋亡的影响。
AIM: to investigate effects of ubiquitin-proteasome inhibitor on proliferation and apoptosis of gastric carcinoma cells.
泛素蛋白酶体途径是调节多种细胞生物学过程的重要机制，也是恶性肿瘤相关调节异常的潜在靶点；
Ubiquitin-proteasome pathway is an important mechanism regulating many processes of cellular biology, and also a potential target for abnormal regulation associated with malignancy.
泛素蛋白酶体途径是真核生物最普遍的调控过程之一。
The ubiquitin-proteasome pathway is now considered as one of the most common regulatory processes in all eukaryotes.
泛素- 蛋白酶体途径介导的蛋白降解是机体调节细胞内蛋白水平与功能的一个重要机制。
Protein degradation mediated by ubiquitin-proteasome pathway is an important mechanism which modulates cellular proteins′ activity and function.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
泛素是一种保守的多肽单元，在泛素蛋白酶体途径中起重要作用。
Ubiquitin is a conserved polypeptide unit that plays an important role in the ubiquitin-proteasome pathway.
通过caspase-3剪切的Actin可能加速泛素/蛋白酶体依赖的肌肉蛋白水解（6）。
Actin cleavage by caspase-3 may accelerate ubiquitin/proteosome dependent muscle proteolysis (6).
通过caspase-3剪切的Actin可能加速泛素/蛋白酶体依赖的肌肉蛋白水解（6）。
Actin cleavage by caspase-3 may accelerate ubiquitin/proteosome dependent muscle proteolysis (6).
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