泛素基因有泛素融合基因和多聚泛素基因两种形式。
The polyubiquitin gene and the ubiquitin extension gene are two kinds of the ubiquitin genes.
目的分析泛素依赖的蛋白水解通路(UPP)在转染了脊髓小脑性共济失调3型(SCA3)基因的PC 12细胞中的定位及作用。
Objective To analyze the role and location of ubiquitin-dependent proteolysis pathway (UPP) in PC12 cells transfected by plasmids with spinocerebellar ataxia type 3 (SCA3) gene.
我们的实验也发现，烧伤脓毒症大鼠骨骼肌内泛素系统的基因和蛋白表达显著增强。
Our study also found that the gene and protein expression of ubiquitin system in skeletal muscle were enhanced during burn sepsis.
目的分离、克隆人泛素结合酶基因，并初步研究其组织表达谱。
Objective To identify and clone the gene encoding human ubiquitin binding enzyme and study its expression spectrum.
目的探讨泛素羧基末端水解酶l1 (uch - L1)基因的S18Y多态性在散发性阿尔茨海默病(AD)发病机制中的作用。
Objectives: To explore the role of S18Y polymorphism of Ubiquitin Carboxy-terminal Hydrolase-L1 (UCH-L1) gene in the pathogenesis of sporadic Alzhermer's disease (AD).
已有的研究表明，水稻基因组数据库中存在48个预测的泛素结合酶基因。
Previous studies showed that there are 48 predicted ubiquitin-conjugating enzyme genes in rice genome.
当研究人员向突变细胞内加入人造泛素——一种组蛋白复合物后，细胞恢复正常，表明这的确是Brca1基因的核心功能。
When the researchers added artificial ubiquitin-histone complexes to the mutant cells, the cells recovered, suggesting this was indeed the Brca1 gene's core function.
蛋白结构域分析表明，水稻泛素结合酶基因主要由一个泛素结合酶催化结构域组成。
Protein domain analysis showed that ubiquitin-conjugating enzyme genes mainly consist of a big ubiquitin-conjugating enzyme catalytic domain.
其余的克隆分别编码尼克酞胺腺嗓吟二核昔酸脱氢酶亚型4、人血清白蛋白、泛素特异性蛋白酶10、翠丸增强基因转录子、激肤酶原。
They encode 14 proteins, nine of which have unknown functions, others include human serum albumin, NADH dehydrogenase subunit 4, ubiquitin specific protease 10, testis enhanced gene transcript.
系统进化树分析表明，48个水稻泛素结合酶基因可分为3个大组，总共7个亚组。
Phylogenetic tree analyses indicate that the 48 rice ubiquitin-conjugating enzyme genes can be divided into 3 groups, 7 sub-groups in total.
感染后肌肉肌纤蛋白基因表达下降，而肌肉泛素蛋白基因表达显著增强。
Expression of muscle myosin heavy chain-1 gene decreased and muscle ubiquitin gene expression increased in sepsis.
本研究确定了主要的组蛋白h 2 A去泛素和表明H2A去泛素化是至关重要参与细胞周期进程和基因表达。
This study identifies the major deubiquitinase for histone H2A and demonstrates that H2A deubiquitination is critically involved in cell cycle progression and gene expression.
泛素- 蛋白酶体通路介导细胞蛋白质的降解，在细胞周期、基因转录及表达、 抗原提呈和炎症演进等方面发挥调控作用。
Ubiquitin-proteasome pathway mediates the degradation of cell protein and modulates cell cycle, gene translation and expression, antigen presentation and inflammation development.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of the DNA damage response and DNA repair.
IAA蛋白的泛素化降解在生长素反应中发挥关键性作用，ARF和AUX/IAA蛋白相互作用调节生长素响应基因的转录。
The degradation of AUX/IAA protein by ubiquitination plays essential role in auxin response, and the interaction between ARF and AUX/IAA protein regulates the transcription of auxin-response genes.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
乳腺癌易感基因，BRCA1，编码一种E3泛素连接酶，BRCA1通过调控DNA损伤反应和DNA修复维持基因组的稳定性。
The breast cancer susceptibility gene, BRCA1, codes for an E3 ubiquitin ligase that functions in the maintenance of genome stability through regulation of DNA damage response and DNA repair.
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