ICV给药不仅使全身浓度降低,还在CNS内获得了更高的治疗有效浓度。
ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.
研究结论证实MPS(多磺酸粘多糖)不但能透皮吸收,而且其活性成分能在各真皮亚层达到有效的治疗浓度。
The results not only confirmed the absorption of MPS but also showed that the active ingredient reaches the individual dermal layers in therapeutic effective concentrations.
基因治疗被认为是维持骨缺损局部生长因子有效治疗浓度最有希望的一种方法。
Gene therapy is considered to maintain bone defect an effective therapeutic concentrations of local growth factor in the most promising methods.
这句话没翻译。试译:叶酸治疗组与安慰剂组比较,血清叶酸浓度增加576%且血浆同型半胱氨酸水平下降26%视为治疗有效。
Treatment was effective with serum folate concentrations increasing by 576% and plasma homocysteine falling by 26% for the folic acid group compared with placebo.
本发明的缓释制剂既能使药物起效迅速,又能长时间维持药物的有效浓度,具有更理想的治疗效果。
The slow-release preparation enables the medicaments to quickly exert the effect, can maintain the effective concentration of the medicaments for a long time and has more ideal curing effect.
但这种给药方式使血药浓度波动很大,不利于临床的有效治疗。
But the administration makes the plasma concentration change enormously, which is not suitable in treatment.
结论:在丙戊酸治疗药物监测中,要关注影响丙戊酸血药浓度的因素,确保患者用药安全有效。
CONCLUSION: in therapeutic drug monitoring of valproate, it should be concerned about the impact factors of valproate concentration to ensure the safety and efficacy in patients.
结论:精准药学服务可有效地为患者提供最佳的给药方案,预测初始治疗剂量及最佳治疗浓度,提高药物治疗效果、减少药品不良反应。
CONCLUSIONS: Precision pharmaceutical care can effectively provide patients with optimal dosing regimens, predict initial dose and optimal therapeutic concentrations, improve efficacy and reduce ADR.
结论微泵注射高浓度氯化钾治疗老年重度低钾血症患者安全、有效。
ConclusionThe high concentrations of potassium chloride with micro-pump injection in treatment of severe hypokalemia in elderly patients is safe and effective.
结论微泵注射高浓度氯化钾治疗老年重度低钾血症患者安全、有效。
ConclusionThe high concentrations of potassium chloride with micro-pump injection in treatment of severe hypokalemia in elderly patients is safe and effective.
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