这些靶基因在乳腺癌细胞核原发瘤中显示了甲基化相关的转录沉默作用。
These target genes displayed methylation - associated transcriptional silencing in breast cancer cells and primary tumours.
DNA甲基可以改变生物的形态，但是最近甲基化在真核生物中的基因沉默作用成为了科研的热点领域。
DNA methylation has a number of epigenetic functions, but the scientific interest has recently focused on the gene silencing effect methylation can have in eucaryotic cells.
目的：构建基质金属蛋白酶9靶向的RNA干扰质粒载体，观察其对小鼠巨噬细胞基质金属蛋白酶9基因表达的沉默作用。
AIM: to construct plasmid vector of RNA interference specific for matrix metalloproteinases (MMP) -9 and observe the silencing effect on gene expression of MMP-9 in macrophage of mice.
筛选工作通过沉默每个基因来评估该基因在药物作用中的功能。
The screen works by silencing each gene in turn to assess its effect on how well the drug works.
在正常细胞中，通过组蛋白标记或DNA包装蛋白，在泛素分子的作用下，BRCA1蛋白使这些区域保持沉默。
In normal cells, the BRCA1 protein keeps these regions silent by tagging histones, or DNA packaging proteins, with a molecule called ubiquitin.
如珍纳斯、设计看起来扶老携幼在同时指示：作为沉默质量全部批量生产品起着至关重要的作用，但私下普遍在我们的生活中；
Like Janus , design looks in tow directions at the same time: as a silent quality of all mass-produced goods it plays a generally unacknowledged but vital role in all our lives;
应用刑事沉默权对刑事侦查行为虽然具有一些消极作用，但从总体上看，是有利于提升刑事侦查行为，推动刑事侦查工作的。
Application of criminal silence right has negative effect on criminal detection behavior but is helpful to improve criminal detection behavior and promote criminal detection work.
本项研究对中国大学英语教师在解读学生的课堂沉默行为、打破课堂沉默、促进师生交流和提高课堂教学效果方面有启示作用。
The study is supposed to help teachers correctly interpret students' classroom silence so that they can break the ice and improve the efficiency of language teaching in classroom.
色彩是沉默无言的，然而却能透过人的眼睛在人的心里沉淀为一种心境，色彩带给人的情感作用是不容忽视的。
The color is wordless, but it can deposit a mood in one's heart through permeating the eyes. The color can arouse the affectivity, which can not be ignored.
就RNA干涉与基因沉默的研究历史、作用机制和应用作了综述。
Here the study history, mechanism and applications of RNAi and gene silencing are reviewed.
DNA甲基化由DNA甲基转移酶催化，在多种调节因子的参与下，与组蛋白修饰相互作用，抑制基因转录，导致基因沉默。
DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription, induce gene silencing at the participation of many regulators.
药物进入癌细胞后，第二个包含沉默rna的模块，开始发挥作用。
With the drug now inside the cancer cell, the second module, which contains silencing RNA, launches its effect.
其作用水平主要有三种：位置效应、转录水平的基因沉默和转录后水平的基因沉默。
The positions where transgene silencing occurs mainly are inserting position? transcriptional gene silencing and posttranscriptional gene silencing.
本文通过病毒防御作用、作用模式、沉默信号的传递特点和植物病毒对转录后基因沉默的抑制作用四方面对植物中转录后基因沉默现象进行综述。
In this paper, the affection of PTGS in virus resistance, PTGS mechanism model, transmission of silence message and suppression of virus protein to PTGS are reviewed.
此外，研究发现，员工的个人背景变量对员工的领导风格感知、组织信任水平和沉默行为有重要的影响作用。
We also found that the employee's personal qualities has great influence on the cognitive of the leadership, the level of organization trust and the employee silence behavior.
这个甲基化作用同基因沉默有关，因为它会导致DNA的双螺旋折叠得更加紧密。
This methylation is associated with gene silencing, as it causes the DNA's double helix to fold even tighter upon itself.
哺乳动物似乎具有利用胞嘧啶甲基化提供一个可继承的机制，用来改变DNA -蛋白质相互作用，辅助这个沉默。
Mammals appear to have taken advantage of the possibilities afforded by cytosine methylation to provide a heritable mechanism for altering DNA-protein interactions to assist in such silencing.
真核生物基因顺式作用元件分为启动子、增强子、沉默子，是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
真核生物基因顺式作用元件分为启动子、增强子、沉默子，是调节基因转录的特定DNA序列。
Eukaryotic gene cis-acting element includes the promoter, enhancer, silencer, which are the specific DNA sequences regulating gene transcription.
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