• 本发明课题开发着色稳定性优异水飞蓟宾糖苷溶液

    The subject of the invention is to develop silybin glucoside solution with excellent coloring stability.

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  • 目的建立高效液相色谱法测定肝泰胶囊水飞蓟宾含量方法。

    OBJECTIVE: To establish an HPLC method for the assaying of silybin in Gantai capsule.

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  • 采用电喷雾离子阱(ESI - MS)谱技术水飞蓟结构裂解途径进行研究。

    The structure and fragmentation pathway of silybin were elucidated by electron spray ionization mass spectrometry (ESI-MS).

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  • 目的观察林佳(水飞蓟磷脂复合物)联合复方丹参滴丸治疗脂肪肝纤维化临床疗效

    OBJECTIVE: To observe the clinical efficacy of silibinin capsules (silibinin phospholipids compound) plus compound Danshen dropping pills for adiposis hepatica and hepatic fibrosis.

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  • 方法应用红外光谱、磷磁共振波谱方法对本室合成水飞蓟卵磷脂复合物进行检测分析

    Methods: the infrared spectrum and nuclear magnetic resonance spectrum of the SLC prepared in the authors' lab were made to analyze the structure of the complex.

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  • 认为,可以找到影响氧化损伤药物虽然我不是确定水飞蓟本身是不是直接抗病毒效果

    I think there is a role to look for drugs that affect oxidative stress although I am not so sure that silibinin does not have a direct antiviral effect itself.

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  • 药效学结果表明该7位取代脱氢水飞蓟宾化合物可以预期用于制备防治神经退行性疾病药物的用途。

    The pharmacodynamic result shows that 7-site substituted dehydrogenized silybin ether can be expectantly used for preparing the medicament for preventing and treating the neurodegenerative diseases.

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  • 方法采用固体分散载体阻滞性高分子材料,使用固体分散球晶制粒相结合的技术制备水飞蓟缓释微球

    Methods Sustained-release silybin microspheres were prepared by the spherical crystallization technique with solid-dispersing and release-retarding polymers.

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  • 研究表明水飞蓟宾具有良好治疗高血脂症消除自由基、抗肝脂质过氧化作用、抗缺血再灌注损伤作用。

    Studies have shown that silibinin also has a good treatment of hyperlipemia, eliminating free radicals, anti-hepatic lipid peroxidation, anti-ischemia-reperfusion injury.

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  • 方法:以滴丸硬度外观、表面光滑度、水飞蓟的含量为评价指标,采用正交试验研究滴丸成型最佳工艺条件

    Methods: the optimum preparation condition were researched by orthogonal test according to the hardness of drop pills, appearance, smooth and the content of silybin.

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  • 非常幸运地研究抗氧化研究,发现非常古老植物治疗药物水飞蓟,它非常有效的非干扰素介导抗病毒作用

    I was lucky in that by doing research on antioxidants to find that a very old plant remedy called silibinin has a very powerful non-interferon mediated action against the virus.

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  • 卵磷脂对水飞蓟抗急性肝损伤具有协同作用,其不仅通过提高水飞蓟宾生物利用度增强药效,而且其自身也具有保肝作用

    The hepatoprotective potential of SPC was improved not only by the improvement of bioavailability of silybin according to complex silybin with PC, also by the synergic action of PC.

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  • 目的探讨酒精脂肪肝病(NAFLD)大鼠模型肝脏线粒体流动性改变以及观察水飞蓟NAFLD的防治作用

    AIM: to explore the effects of silybin on mitochondrial membrane fluidity in the rats with non-alcoholic fatty liver disease (NAFLD).

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  • 结果水飞蓟卵磷脂复合物具有水飞蓟卵磷脂红外光谱特征磁共振波谱显示水飞蓟宾和卵磷脂间以共价键结合。

    Results: SLC possesses the characteristics of the infrared spectrum of silybin and lecithin, its nuclear magnetic resonance spectrum showed that SLC was combined by non covalent bond.

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  • 结果水飞蓟卵磷脂复合物具有水飞蓟卵磷脂红外光谱特征磁共振波谱显示水飞蓟宾和卵磷脂间以共价键结合。

    Results: SLC possesses the characteristics of the infrared spectrum of silybin and lecithin, its nuclear magnetic resonance spectrum showed that SLC was combined by non covalent bond.

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