本文概述了水通道蛋白的发现和其对水分子的筛选传输机理。
This review summarizes the discovery of water channel proteins and their mechanism of water-specific transport.
水通道蛋白是对水专一的通道蛋白,普遍存在于动、植物及微生物中。
Aquaorins are integral membrane proteins occurring in mammals, plants, and microorganisms, which serve as channels that permit the bidirectional passage of water through cellular membranes.
除此之外,水通道蛋白还参与细胞的增殖、迁移和凋亡等一些重要生命活动。
Recent studies indicated that AQPs play a role in the physiological processes of tumor angiogenesis, cell migration and apoptosis.
水通道蛋白表达的异常已被证实与临床许多疾病有密切关系,因此其表达的调节及调节机制也至关重要。
The abnormal expression of AQPs have been confirmed to have close relationship with many clinical diseases, therefore its expression and regulation is also very important.
结论人类皮肤供水系统缺陷可能与年龄有关,水通道蛋白在维持皮肤正常生理功能等方面具有重要意义。
Conclusions The deficiency of water providing system in human skin may be related to age. Moreover, AQPs play an important role in maintaining normal physiological and functional properties of skin.
目的观察重型脑损伤后水通道蛋白- 4 (AQP4)表达变化,及其与脑损伤后脑水肿之间的关系。
Objective To investigate the changes of AQP4 expression after traumatic brain injury (TBI), and the relationship between the brain edema and AQP4 expression.
目的克隆大鼠水通道蛋白4(AQP4)M23基因并构建其载体为进一步研究提供理论基础和研究工具。
Purpose: AQP4 M23 gene cloning and construction in the expression vector can provide us a research tool.
本文从水通道蛋白,钙通道,钠通道,钾通道等多种通道蛋白引起的遗传病的现象以及机理做较深入的阐述。
In this thesis, phenomena and mechanism of genetic diseases caused by many channel proteins, such as aquatic, calcium, sodium channels, potassium channel proteins, are discussed elaborately.
本文从水通道蛋白,钙通道,钠通道,钾通道等多种通道蛋白引起的遗传病的现象以及机理做较深入的阐述。
In this thesis, phenomena and mechanism of genetic diseases caused by many channel proteins, such as aquatic, calcium, sodium channels, potassium channel proteins, are...
研究表明,多种恶性肿瘤存在水通道蛋白的异常表达,水通道蛋白在肿瘤的增殖、浸润转移中具有重要作用。
Studies have shown that AQPs are strongly expressed in neoplasm of different origins, and they may play important roles in cell proliferation and migration of agressisve tumor.
结论牛角膜内皮细胞中的水通道蛋白- 1在角膜内皮液体转运中起着重要作用,其表达改变可能导致角膜水肿和功能改变。
Conclusion AQP-1 in CBCEC play an important role in corneal endothelial cell's fluid transport, its expression change may cause corneal edema and function disorder.
结论:水通道蛋白1和血管内皮生长因子在视网膜缺血性疾病中起着重要的作用,二者可能共同影响了视网膜的水代谢过程。
CONCLUSION: AQP1 and VEGF may play an important role in various blinding ischemic ocular diseases, and coeffect the water metabolism of retina.
纳米管的作用可能类似于天生的蛋白质通道,用来帮助水进出细胞。
Possibly, the nanotubes are acting as analogues of the natural protein channels that pump water in and out of cells.
纳米管的作用可能类似于天生的蛋白质通道,用来帮助水进出细胞。
Possibly, the nanotubes are acting as analogues of the natural protein channels that pump water in and out of cells.
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