在碱性条件下，用氨基乙酸与二硫化碳、氯甲酸乙酯反应合成了异硫氰基乙酸乙酯，总收率为4 8。
Isothiocyanatoacetate ester is synthesized by the reaction of aminoacetic acid with carbon disulfide and ethyl chloroformate in the presence of an alkali with the overall yield of 48.
方法原甲酸三乙酯与氰乙酸乙酯缩合，然后和羟乙基肼经环合、水解等一锅法合成5-氨基吡唑-4-甲酸，然后在亚硫酸钠存在条件下加热脱羧得到5-氨基-1-羟乙基吡唑。
METHODS 5-amino-1-hydroxyethyl pyrazole-4-carboylic acid was synthesized through condensation of ethyl cyanoacetate and triethyl orthoformate followed by one-pot methodology of cyclization, hydolysis.
方法原甲酸三乙酯与氰乙酸乙酯缩合，然后和羟乙基肼经环合、水解等一锅法合成5-氨基吡唑-4-甲酸，然后在亚硫酸钠存在条件下加热脱羧得到5-氨基-1-羟乙基吡唑。
METHODS 5-amino-1-hydroxyethyl pyrazole-4-carboylic acid was synthesized through condensation of ethyl cyanoacetate and triethyl orthoformate followed by one-pot methodology of cyclization, hydolysis.
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