结论氯沙坦能下调AT1R的表达。
Conclusion Losartan can down-regulate the expression of AT1R.
氯沙坦可以减轻雷帕霉素所致的大量蛋白尿。
Furthermore, losartan can alleviate severe proteinuria induced by rapamycin.
结论：氯沙坦抗动脉粥样硬化机制与血脂无关。
Conclusion the mechanism of losartan in preventing atherosclerosis has little to do with lipid.
推测氯沙坦能减轻阿霉素肾病大鼠的肾脏损害。
Losartan can reduce kidney lesions in adriamycin-induced nephropathy in rats.
目的研究氯沙坦对老年收缩期高血压的临床作用。
Objective: to investigate the efficacy of losartan in the treatment of older patient with isolated systolic hypertension.
目的：评价氯沙坦对高血压左心室肥厚的逆转作用。
Objective: To evaluate the effect of losartan on left ventricular hypertrophy reversal.
目的观察氯沙坦的降压作用及其对心率变异性的影响。
Objective To observe the effect of losartan on hypertension and the heart rate variability.
目的：观察氯沙坦对老年高血压患者心肾功能的影响。
Objective To investigate the clinical effects of Losartan on ventricular and renal functions in elderly hypertensive patients.
结论：替米沙坦减轻糖尿病肾病患者蛋白尿优于氯沙坦。
CONCLUSION Telmisartan is superior to losartan in reducing proteinuria in diabetic nephropathy patients with hypertension, despite a similar reduction in blood pressure.
目的：观察氯沙坦降压疗效及其对部分血管活性肽的影响。
AIM: To investigate the effect of losartan on blood pressure, vascular active peptides in patients with essential hypertension.
结论氯沙坦、培多普利可以减轻左室重构，改善心功能障碍。
CONCLUSION Losartan and Perindopril could improve the left ventricular remodeling and heart functions in AMI rats.
目的氯沙坦钾对糖尿病肾病慢性肾功能不全患者肾功能的影响。
Objective To observe the effect of losartan potassium on renal function of the NIDDM hypertensive patients with chronic renal failure (CRF).
目的观察氯沙坦与波依定联合用药治疗慢性肾衰竭并高血压的效果。
ObjectiveTo observe the effects of combination of losartan and plendil for patients with chronic renal failure complicated hypertension.
目的评价氯沙坦在治疗慢性肾功能不全伴高血压时对肾脏的保护作用。
Objective To evaluate the renal protective effects of losartan in treatment of chronic renal impairment.
目的探讨氯沙坦治疗轻、中度原发性高血压的疗效和对尿清蛋白的影响。
Objective To investigate the efficacy and antiproteinuric effect of losartan in the treatment of mild to moderate essential hypertension.
慢性咳嗽在依那普利组有12例、在氯沙坦组有6例而安慰剂组有4例。
Chronic cough occurred in 12 patients receiving enalapril, 6 receiving losartan, and 4 receiving placebo.
目的：评价并比较氯沙坦及氨氯地平的降压疗效及对左室肥厚的逆转作用。
AIM: To evaluate and compare losartan and amlodipine on the hypotensive effect and reverse reduction of left ventricular hypertrophy.
氯沙坦治疗可以明显降低血浆炎症因子水平，有利于动脉粥样硬化斑块稳定。
Losartan treatment can obviously decrease the plasma level of inflammatory factors, and it is good for the stability of atherosclerotic plaques.
目的：探讨氯沙坦对老年中重度原发性高血压患者内皮素和一氧化氮的影响。
Objective: To investigate the effect of losartan on plasma endothelins (ET) and nitrogen mon oxide (NO) in elderly patients with moderate to severe essential hypertension.
结论卡托普利和氯沙坦均具有改善血管性痴呆模型大鼠学习记忆能力的作用。
Conclusion captopril and losartan can improve the ability of learning and memory of the rats with vascular dementia.
目的研究和观察氯沙坦对肾功能不全的高血压患者的降压作用及对肾脏的影响。
Objective TO research the effect of Losartan on hypertension with renal failure and the influence on kidney.
目的评价氯沙坦钾胶囊与氯沙坦钾片在中国健康成年男性志愿者中的生物等效性。
Objective To evaluate the bioequivalence of losartan potassium capsules and tablets in healthy Chinese male volunteers.
目的：比较福辛普利和氯沙坦治疗心力衰竭的疗效及对肾素血管紧张肽系统的影响。
AIM: to compare the clinical efficacy of fosinopril and losartan in the treatment of heart failure and its influence to the renin angiotensin system.
目的探讨氯沙坦对高血压左室肥厚(LVH)的逆转及左室收缩和舒张功能的影响。
Objective to investigate the effects of Losartan on hypertensive left ventricular hypertrophy (LVH) and left ventricular systolic and diastolic functions.
目的：合成抗高血压药氯沙坦的关键中间体2-正丁基-4-氯-5-甲酰基咪唑。
Objective:To synthesize a key intermediate of anti-hypertension drug Losartan, 2-butyl-4-chloro-5-formylimidazole(1).
氯沙坦肾显像是一种较新的诊断rvh的无创伤性方法，具有一定的灵敏度和准确性。
The losartan renography is a relatively new non-invasive method for diagnosing RVH, with definite sensitivity and specificity.
目的：比较伊贝沙坦和氯沙坦治疗轻中度高血压病的临床疗效、安全性及治疗依从性。
Objective: to compare the effects, safety and therapeutic dependence of irbesartan with that of losartan on mild-to-moderate essential hypertension.
目的：探讨福辛普利和氯沙坦对自发性高血压（SHR）大鼠脂肪组织脂联素的影响。
Objective:To observe the impacts of fosinopril and losartan on adiponectin expression in adipose tissue of vascular walls of spontaneously hypertensive rats(SHR).
结论低剂量的氯沙坦和叶酸能有效的改善血液流变学，保护血管内皮，防止血管重构。
CONCLUSION Losartan-Folic acid could be used to decrease the viscosity, protect vascular endothelium and reversing vascular reconstruction.
目的比较福辛普利与氯沙坦治疗冠心病心衰伴慢性阻塞性肺部疾病的长期疗效和安全性。
Objective To compare the long term safety and efficacy of fosinopril and losartan in the treatment of ischemic heart failure with chronic obstructive pulmonary disease(COPD).
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